Occupational ultraviolet exposure and risk of non-Hodgkin's lymphomas: a meta-analysis.
Occupational ultraviolet exposure and risk of non-Hodgkin's lymphomas: a meta-analysis.
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DOI：
10.18632/oncotarget.18140
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发表时间：
2017-09-22
期刊：
影响因子：
--
通讯作者：
Zhang S
中科院分区：
文献类型：
--
作者：
Lu D;Xu F;Hu K;Yin L;Duan H;Zhang J;Zhang S
非霍奇金淋巴瘤是一种异质性的淋巴细胞增生性疾病。我们进行了一项荟萃分析，以总结病例对照研究和队列研究中关于职业性日晒与非霍奇金淋巴瘤风险之间不一致关联的现有证据。我们检索了PubMed， ISI web of science, Cochrane Library， EMBASE和相关文章的参考文献列表。研究特定的优势比或相对风险和95%置信区间通过使用固定效应或随机效应模型进行汇总。meta分析包括10项病例对照研究和1项队列研究。总体而言，职业性紫外线照射与非霍奇金淋巴瘤风险的合并优势比为1.15（95%可信区间：0.99,1.32;I2 = 44.4%）。在高加索人群中，职业性日晒与NHL风险呈正相关，为1.14（95%可信区间：1.05,1.23;2=25.4%，p为异质性=0.202）。非霍奇金淋巴瘤的常见亚型和紫外线照射均为阴性。t细胞非霍奇金淋巴瘤的合并优势比为1.16(95%可信区间：0.90,1.50)；b细胞非霍奇金淋巴瘤为0.79(95%可信区间：0.61,1.02)；1.13,(95%可信区间：0.96,1.34)；男性为1.25,(95%可信区间：0.95,1.64)；1.49,（95%可信区间：0.99,2.25）。资料显示职业性紫外线照射是白种人非霍奇金淋巴瘤的危险因素。而职业性紫外线照射与普通人群及非霍奇金淋巴瘤常见亚型的非霍奇金淋巴瘤发病风险无相关性。此外，性别特异性职业日晒也显示与非霍奇金淋巴瘤的风险无关联。
Non-Hodgkin lymphoma is a heterogeneous group of lympho-proliferative disorders. We performed a meta-analysis to summarize the available evidence from case-control studies and cohort study on the inconsistent association between occupational sun exposure and the risk of non-Hodgkin lymphoma. We searched PubMed, ISI web of science, the Cochrane Library, EMBASE and reference lists for relevant articles. Study specific odds ratios or relative risk and 95% confidence intervals were pooled by using fixed-effects or random-effects models. Ten case-control studies and one cohort study were included in the meta-analysis. Overall, the pooled odds ratios for occupational ultraviolet exposure and non-Hodgkin lymphoma risk was 1.15(95% confidence intervals: 0.99, 1.32; I2 = 44.4%). Occupational sun exposure was positively associated with the risk of NHL 1.14 (95% confidence intervals: 1.05, 1.23; I2=25.4% p for heterogeneity =0.202) in Caucasian population. Common subtypes of non-Hodgkin lymphoma and ultraviolet exposure had the negative results. The pooled odds ratios was 1.16, (95%confidence intervals: 0.90, 1.50) for T-cell non-Hodgkin lymphoma; 0.79, (95%confidence intervals: 0.61, 1.02) for B-cell non-Hodgkin lymphoma; 1.13, (95%confidence intervals: 0.96, 1.34) for chronic lymphocytic leukemia; 1.25, (95%confidence intervals: 0.95, 1.64) for males; 1.49, (95%confidence intervals: 0.99, 2.25) for females. Data suggested that occupational ultraviolet exposure was a risk factor for non-Hodgkin lymphoma in Caucasian population. While, there had no relationship between occupational ultraviolet exposure and risk of non-Hodgkin lymphoma in general population as well as non-Hodgkin lymphoma common subtypes. Besides, gender specific occupational sun exposure also indicated no association on risk of non-Hodgkin lymphoma.
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影响因子：
2.3
作者：
Kelly, Jennifer L.;Drake, Matthew T.;Fredericksen, Zachary S.;Asmann, Yan W.;Liebow, Mark;Shanafelt, Tait D.;Feldman, Andrew L.;Ansell, Stephen M.;Macon, William R.;Herr, Megan M.;Wang, Alice H.;Nowakowski, Grzegorz S.;Call, Timothy G.;Habermann, Thomas M.;Slager, Susan L.;Witzig, Thomas E.;Cerhan, James R.
通讯作者：
Cerhan, James R.
DOI：
10.1097/jom.0b013e3181be6bfe
发表时间：
2009-12-01
影响因子：
3.2
作者：
Karunanayake, Chandima P.;Singh, Gayatri V.;Pahwa, Punam
通讯作者：
Pahwa, Punam
影响因子：
7.7
作者：
Boffetta, Paolo;van der Hel, Olga;Brennan, Paul
通讯作者：
Brennan, Paul
影响因子：
20.3
作者：
Chang, Ellen T.;Canchola, Alison J.;Horn-Ross, Pamela L.
通讯作者：
Horn-Ross, Pamela L.
影响因子：
--
作者：
Freedman, DM;Zahm, SH;Dosemeci, M
通讯作者：
Dosemeci, M