Measuring Memory Reactivation With Functional MRI: Implications for Psychological Theory.
Measuring Memory Reactivation With Functional MRI: Implications for Psychological Theory.
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DOI：
10.1177/1745691612469031
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发表时间：
2013-01
期刊：
影响因子：
--
通讯作者：
Wagner AD
中科院分区：
文献类型：
--
作者：
Levy BJ;Wagner AD
环境线索经常让我们想起以前的经历，这些线索会触发对过去事件的记忆的重新激活。最近的证据表明，使用功能性核磁共振成像可以观察到记忆的重新激活，分布式模式分析甚至可以在单个试验中提供重新激活的证据。测量记忆再激活的能力为认知心理学长期感兴趣的理论问题提供了独特而有力的杠杆作用，提供了一种解决已被证明仅凭行为数据难以回答的问题的方法。这里我们考虑三个实例。首先，再激活措施可以表明基于记忆的推理（即概括）是通过整合跨事件表征的编码还是通过可分离事件记忆的灵活表达产生的。其次，在线记忆再激活的测量可以通过提供关于在竞争性检索情境中竞争性记忆何时被重新激活的信息来为遗忘理论提供信息。最后，神经再激活可能为重放在记忆巩固中的作用提供了一个窗口。跟踪记忆再激活的能力，包括在个体试验层面，提供了行为测量无法提供的独特杠杆，因此有望揭示诸如概括、整合、遗忘和巩固等各种主题。
Environmental cues often remind us of earlier experiences, with cues triggering the reactivation of memories of events past. Recent evidence suggests that memory reactivation can be observed using functional MRI, and that distributed pattern analyses can even provide evidence of reactivation on individual trials. The ability to measure memory reactivation offers unique and powerful leverage on theoretical issues of long-standing interest in cognitive psychology, providing a means to address questions that have proven difficult to answer with behavioral data alone. Here we consider three instances. First, reactivation measures can indicate whether memory-based inferences (i.e., generalization) arise through the encoding of integrated cross-event representations or through the flexible expression of separable event memories. Second, online measures of memory reactivation may inform theories of forgetting by providing information about when competing memories are reactivated during competitive retrieval situations. Finally, neural reactivation may provide a window onto the role of replay in memory consolidation. The ability to track memory reactivation, including at the individual trial level, provides unique leverage that is not afforded by behavioral measures, and thus promises to shed light on such varied topics as generalization, integration, forgetting, and consolidation.
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影响因子：
25
作者：
Kuhl, Brice A.;Dudukovic, Nicole M.;Wagner, Anthony D.
通讯作者：
Wagner, Anthony D.
DOI：
10.1037/0278-7393.25.6.1403
发表时间：
1999-11-01
影响因子：
2.6
作者：
Ciranni, MA;Shimamura, AP
通讯作者：
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影响因子：
25
作者：
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通讯作者：
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DOI：
10.1016/j.cub.2010.01.053
发表时间：
2010-03-23
期刊：
Current biology : CB
影响因子：
--
作者：
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通讯作者：
Maguire EA
影响因子：
16.2
作者：
Johnson, Jeffrey D.;McDuff, Susan G. R.;Rugg, Michael D.;Norman, Kenneth A.
通讯作者：
Norman, Kenneth A.