Bladder and bowel symptoms in cervical and endometrial cancer survivors.

Bladder and bowel symptoms in cervical and endometrial cancer survivors.
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DOI:
10.1002/pon.3461
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发表时间:
2014-06
期刊:
影响因子:
3.6
通讯作者:
Wyman, Jean F.
Wyman, Jean F.
中科院分区:
医学2区
文献类型:
--
作者:
Donovan, Kristine A.;Boyington, Alice R.;Judson, Patricia L.;Wyman, Jean F.

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以前的研究可能低估了妇科癌症幸存者肠道和膀胱症状的患病率。我们试图估计这些症状在宫颈癌和子宫内膜癌幸存者中的患病率,与非癌症对照组相比,这些幸存者在一年前完成了治疗,并检查与幸存者更严重症状相关的因素。作为一项更大的生活质量研究的一部分,宫颈癌或子宫内膜癌治疗后一年的幸存者(n = 104)完成了膀胱和肠道症状的测量。招募了年龄和种族/民族匹配的无癌症史的女性样本进行比较。幸存者报告膀胱症状,特别是储尿和失禁症状的患病率高于非癌症对照组。幸存者肠道症状的患病率高于以往研究报告的患病率。更严重的症状与年龄较小、年收入较低和受教育程度较低有关。其他相关因素包括较高的体重指数和吸烟史。据推测,更严重的症状与根治性子宫切除术和盆腔放疗有关。膀胱和肠道症状在宫颈癌和子宫内膜癌幸存者中比非癌症对照组更普遍。未来的研究应该在更大的前瞻性研究中复制这些发现。
Previous studies likely underestimate the prevalence of bowel and bladder symptoms in gynecologic cancer survivors. We sought to estimate the prevalence of these symptoms in cervical and endometrial cancer survivors who had completed treatment one year previously compared to non-cancer controls, and to examine factors associated with more severe symptoms in survivors. As part of a larger quality of life study, survivors who were one-year post-treatment for cervical or endometrial cancer (n = 104) completed measures of bladder and bowel symptoms. An age- and race/ethnicity-matched sample of women with no history of cancer was recruited for comparison purposes. Survivors reported a higher prevalence of bladder symptoms, specifically storage and incontinence symptoms, than non-cancer controls. Prevalence rates for bowel symptoms in survivors were higher than those reported in previous studies. Greater symptom severity was associated with younger age, lower annual incomes and less education. Other correlates included higher body mass index and history of smoking. As hypothesized, more severe symptoms were associated with radical hysterectomy and pelvic radiation. Bladder and bowel symptoms are more prevalent in cervical and endometrial cancer survivors than non-cancer controls. Future research should replicate these findings in a larger, prospective study.
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