Antibiotics in dust originating from a pig-fattening farm: a new source of health hazard for farmers?

Antibiotics in dust originating from a pig-fattening farm: a new source of health hazard for farmers?
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DOI:
10.1289/ehp.6288
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发表时间:
2003-10
影响因子:
10.4
通讯作者:
Hartung J
Hartung J
中科院分区:
环境科学与生态学1区
文献类型:
--
作者:
Hamscher G;Pawelzick HT;Sczesny S;Nau H;Hartung J

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猪舍灰尘来源于饲料、垫料、粪便和动物本身。如果动物接受抗生素等药物,这些物质的残留物可能会出现在粪便中,空气中或相应动物房的表面上。在一项回顾性研究中,我们调查了20年来从同一猪舍收集的灰尘样本中各种抗生素的发生情况。在90%的样本中,我们检测到多达五种不同的抗生素,包括泰乐菌素,各种四环素,磺胺二甲嘧啶和氯霉素,总量高达12.5 mg/kg灰尘。由于微生物、内毒素和过敏原含量高,动物圈养建筑中的高粉尘暴露被认为是呼吸系统健康危害。吸入被抗生素混合物污染的灰尘可能会产生进一步的风险。除此之外,我们的数据为兽药进入环境的新途径提供了第一个证据。
Pig-house dust originates from feed, bedding, feces, and the animals themselves. If the animals receive drugs such as antibiotics, residues of these substances may occur in manure, in the air, or on surfaces of the respective animal house. In a retrospective study, we investigated dust samples collected during two decades from the same piggery for the occurrence of various antibiotics. In 90% of these samples, we detected up to five different antibiotics, including tylosin, various tetracyclines, sulfamethazine, and chloramphenicol, in total amounts up to 12.5 mg/kg dust. High dust exposure in animal confinement buildings is believed to be a respiratory health hazard because of the high content of microorganisms, endotoxins, and allergens. Further risks may arise from the inhalation of dust contaminated with a cocktail of antibiotics. Apart from that, our data provide first evidence for a new route of entry for veterinary drugs in the environment.
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