Theta sequences of grid cell populations can provide a movement-direction signal.

Theta sequences of grid cell populations can provide a movement-direction signal.
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DOI:
10.1016/j.cobeha.2017.08.012
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发表时间:
2017-10
影响因子:
5
通讯作者:
Leutgeb S
Leutgeb S
中科院分区:
心理学2区
文献类型:
--
作者:
Zutshi I;Leutgeb JK;Leutgeb S

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有人提出,哺乳动物的路径整合是由内部产生的速度和方向输入到网格单元的收敛。虽然这一假设得到了以下发现的支持:头部方向、速度和网格细胞在内嗅皮层中是混合的,以及最近发现头部方向输入对于网格放电是必要的,但网格细胞如何产生的许多细节仍然是难以捉摸的。例如,对记录数据的分析表明,用磁头方向代替移动方向会产生妨碍网格图案形成的误差。为了解决这种差异,我们建议,网格网络的组织使得它似乎运动方向信号是从网格单元的输出,时间上精确的网格单元序列提供了一个强大的方向信号,其他空间和方向的细胞类型。
It has been proposed that path integration in mammals is performed by the convergence of internally generated speed and directional inputs onto grid cells. Although this hypothesis has been supported by the discovery that head direction, speed, and grid cells are intermixed within entorhinal cortex and by the recent finding that head-direction inputs are necessary for grid firing, many details on how grid cells are generated have remained elusive. For example, analysis of recording data suggests that substituting head direction for movement direction accrues errors that preclude the formation of grid patterns. To address this discrepancy, we propose that the organization of grid networks makes it plausible that movement-direction signals are an output from grid cells and that temporally precise grid cell sequences provide a robust directional signal to other spatial and directional cell types.
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