Dopaminergic modulation of incentive motivation in adolescence: age-related changes in signaling, individual differences, and implications for the development of self-regulation.
Dopaminergic modulation of incentive motivation in adolescence: age-related changes in signaling, individual differences, and implications for the development of self-regulation.
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青春期激励动机的多巴胺能调节：信号传导，个体差异以及对自我调节发展的影响的年龄相关的变化。
DOI：
10.1037/a0027432
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发表时间：
2012-05
影响因子：
4
通讯作者：
Collins, Paul F.
中科院分区：
文献类型：
--
作者：
Luciana, Monica;Wahlstrom, Dustin;Porter, James N.;Collins, Paul F.
相对于童年和成年，与激励-回报动机相关的行为激活在青春期增加。这种二次发展模式通常得到行为和实验神经科学研究结果的支持。我们认为，专注于多巴胺神经传递的变化是有益的，在理解这种青少年增加奖励相关的行为激活和随后下降到成年期的机制。我们目前的证据表明，激励奖励动机是由mesoalbens多巴胺调制，它在青春期增加下降到成年之前，由于在分子水平上的规范性发展变化。功能性中脑多巴胺传输的变化的潜在机制进行了讨论，重点是紧张和阶段性的DA传输模式之间的相互作用，在调制一般的激励动机的偏见和奖励学习的功效，在暴露于新的奖励经验。个体差异因素和这些年龄相关的趋势之间的相互作用进行了讨论。
Behavioral activation that is associated with incentive-reward motivation increases in adolescence relative to childhood and adulthood. This quadratic developmental pattern is generally supported by behavioral and experimental neuroscience findings. We suggest that a focus on changes in dopamine neurotransmission is informative in understanding the mechanism for this adolescent increase in reward-related behavioral activation and subsequent decline into adulthood. We present evidence to indicate that incentive-reward motivation is modulated by mesoaccumbens dopamine and that it increases in adolescence before declining into adulthood due to normative developmental changes at the molecular level. Potential mechanisms of variation in functional mesoaccumbens dopamine transmission are discussed with a focus on the interplay between tonic and phasic modes of DA transmission in modulating both general incentive-motivational biases and the efficacy of reward learning during exposure to novel reward experiences. Interactions between individual difference factors and these age-related trends are discussed.
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影响因子：
3.7
作者：
Bramen, Jennifer E.;Hranilovich, Jennifer A.;Sowell, Elizabeth R.
通讯作者：
Sowell, Elizabeth R.
DOI：
10.1111/j.1532-7795.2010.00712.x
发表时间：
2011-03-01
期刊：
Journal of research on adolescence : the official journal of the Society for Research on Adolescence
影响因子：
--
作者：
Casey B;Jones RM;Somerville LH
通讯作者：
Somerville LH
影响因子：
16.2
作者：
Cagniard, Barbara;Beeler, Jeff A.;Zhuang, Xiaoxi
通讯作者：
Zhuang, Xiaoxi
影响因子：
5.3
作者：
Bjork, JM;Knutson, B;Hommer, DW
通讯作者：
Hommer, DW
DOI：
10.1016/j.jaac.2010.08.017
发表时间：
2010-12
影响因子：
13.3
作者：
Casey BJ;Jones RM
通讯作者：
Jones RM