Murine b7-h3 is a co-stimulatory molecule for T cell activation.
Murine b7-h3 is a co-stimulatory molecule for T cell activation.
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鼠 b7-h3 是 T 细胞激活的共刺激分子。
DOI:
10.1089/mab.2013.0052
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发表时间:
2013-12
期刊:
影响因子:
--
通讯作者:
Feng, Ping
中科院分区:
文献类型:
--
作者:
He, Chunyan;Qin, Chenhao;Zhang, Xueguang;Feng, Ping
The B7 family member B7-H3 (CD276) plays a key role during an immune response but its function remains controversial. In this study, we found that murine B7-H3 up-regulated the proliferation and cytokine production of T cells. Our study suggested that there was no interaction of murine B7-H3 with a triggering receptor expressed on myeloid cells (TREM)-like transcript 2 (TLT-2). Further studies demonstrated that mouse B7-H3 specifically bound to T cells and its receptor was not murine TLT-2. Moreover, murine B7-H3 was a positive co-stimulatory molecule in the regulation of T cell-mediated immune responses.
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影响因子:
4.4
作者:
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通讯作者:
Chen, LP
影响因子:
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作者:
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通讯作者:
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影响因子:
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作者:
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影响因子:
4.4
作者:
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通讯作者:
Dong, C
DOI:
10.1158/1078-0432.ccr-08-0536
发表时间:
2008-08-15
期刊:
Clinical cancer research : an official journal of the American Association for Cancer Research
影响因子:
--
作者:
Crispen PL;Sheinin Y;Roth TJ;Lohse CM;Kuntz SM;Frigola X;Thompson RH;Boorjian SA;Dong H;Leibovich BC;Blute ML;Kwon ED
通讯作者:
Kwon ED