Prenatal androgen exposure and children's aggressive behavior and activity level.
Prenatal androgen exposure and children's aggressive behavior and activity level.
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DOI：
10.1016/j.yhbeh.2017.09.012
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发表时间：
2017-11
影响因子：
3.5
通讯作者：
Hines M
中科院分区：
文献类型：
--
作者：
Spencer D;Pasterski V;Neufeld S;Glover V;O'Connor TG;Hindmarsh PC;Hughes IA;Acerini CL;Hines M
男性和女性的一些人类行为（包括攻击性和活动水平）平均有所不同。在这里，我们报告了两项研究的结果，调查了产前雄激素与儿童的攻击性和活动水平之间可能的关系。在研究 1 中，将 43 名年龄 4 至 11 岁、患有先天性肾上腺增生症（CAH，一种导致产前开始肾上腺雄激素分泌增加的遗传性疾病）的 43 名女孩和 38 名男孩的攻击性和活动水平得分与年龄相仿、未受影响的亲属（41 名女孩，31 名男孩）进行了比较。患有 CAH 的女孩在攻击性方面的得分高于未受影响的女孩 (d = 0.69)，而未受影响的男孩在活动水平方面的得分高于未受影响的女孩 (d = 0.50)。其他组间无显着差异。对于研究 2，在 3 至 5 岁的正常发育儿童（48 名女孩，44 名男孩）中调查了羊水睾酮与攻击性和活动水平的关系。男孩在攻击性（d = 0.41）和活动水平（d = 0.50）方面的得分高于女孩。然而，羊水睾酮水平并不是男女攻击性或活动水平的显着预测因子。这两项研究的结果为产前雄激素暴露对儿童攻击性行为（但不是活动水平）的影响提供了一些支持。羊水睾酮的性别内差异可能不足以可靠地评估与攻击性或活动水平的关系。
Some human behaviors, including aggression and activity level, differ on average for males and females. Here we report findings from two studies investigating possible relations between prenatal androgen and children’s aggression and activity level. For study 1, aggression and activity level scores for 43 girls and 38 boys, aged 4 to 11 years, with congenital adrenal hyperplasia (CAH, a genetic condition causing increased adrenal androgen production beginning prenatally) were compared to those of similarly-aged, unaffected relatives (41 girls, 31 boys). Girls with CAH scored higher on aggression than unaffected girls, d = 0.69, and unaffected boys scored higher on activity level than unaffected girls, d = 0.50. No other group differences were significant. For study 2, the relationship of amniotic fluid testosterone to aggression and activity level was investigated in typically-developing children (48 girls, 44 boys), aged 3 to 5 years. Boys scored higher than girls on aggression, d = 0.41, and activity level, d = 0.50. However, amniotic fluid testosterone was not a significant predictor of aggression or activity level for either sex. The results of the two studies provide some support for an influence of prenatal androgen exposure on children’s aggressive behavior, but not activity level. The within-sex variation in amniotic fluid testosterone may not be sufficient to allow reliable assessment of relations to aggression or activity level.
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影响因子：
3.5
作者：
Bergman, Kristin;Glover, Vivette;Sarkar, Pampa;Abbott, Dave H.;O'Connor, Thomas G.
通讯作者：
O'Connor, Thomas G.
影响因子：
1.5
作者：
Brace, RA
通讯作者：
Brace, RA
影响因子：
2.4
作者：
GRIMSHAW, GM;BRYDEN, MP;FINEGAN, JAK
通讯作者：
FINEGAN, JAK
DOI：
10.1016/j.beem.2009.11.005
发表时间：
2010-04-01
影响因子：
7.4
作者：
Cohen-Kettenis, P. T.
通讯作者：
Cohen-Kettenis, P. T.
影响因子：
6.2
作者：
Auyeung B;Ahluwalia J;Thomson L;Taylor K;Hackett G;O'Donnell KJ;Baron-Cohen S
通讯作者：
Baron-Cohen S