A DNA crystal designed to contain two molecules per asymmetric unit.

A DNA crystal designed to contain two molecules per asymmetric unit.
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DOI:
10.1021/ja104833t
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发表时间:
2010-11-10
影响因子:
15
通讯作者:
Seeman, Nadrian C.
Seeman, Nadrian C.
中科院分区:
化学1区
文献类型:
--
作者:
Wang, Tong;Sha, Ruojie;Birktoft, Jens;Zheng, Jianping;Mao, Chengde;Seeman, Nadrian C.

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我们描述了自组装的DNA晶体,每个不对称单元包含两个张拉整体三角形分子。我们用X射线晶体学测定了它的晶体结构。此外,我们还证明了通过将Cy 3染料(粉红色)或Cy 5染料(蓝绿色)附着到晶体成分上来控制晶体的颜色,从而产生相应颜色的晶体。将这对染料连接到这对分子上会产生紫色晶体。
We describe the self-assembly of a DNA crystal that contains two tensegrity triangle molecules per asymmetric unit. We have used X-ray crystallography to determine its crystal structure. In addition, we have demonstrated control over the colors of the crystals by attaching either Cy3 dye (pink) or Cy5 dye (blue-green) to the components of the crystal, yielding crystals of corresponding colors. Attaching the pair of dyes to the pair of molecules yields a purple crystal.
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