Nutrition in Gynecological Diseases: Current Perspectives.

Nutrition in Gynecological Diseases: Current Perspectives.
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DOI:
10.3390/nu13041178
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发表时间:
2021-04-02
期刊:
影响因子:
5.9
通讯作者:
Ali M
Ali M
中科院分区:
医学2区
文献类型:
--
作者:
Ciebiera M;Esfandyari S;Siblini H;Prince L;Elkafas H;Wojtyła C;Al-Hendy A;Ali M

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饮食和营养对于维持人口的整体健康(包括妇女的健康)至关重要。营养缺乏会影响健康状况,反之亦然。基因与营养素的相互作用是健康管理和疾病预防的重要贡献者。营养可以通过多种机制改变基因表达以及对包括癌症在内的疾病的易感性。妇科疾病泛指涉及女性生殖系统的疾病,包括良性肿瘤、恶性肿瘤、感染、内分泌疾病等。子宫肌瘤、子宫内膜异位症等良性疾病十分常见,对女性的生活质量造成负面影响,而恶性肿瘤则是近年来最常见的死亡原因之一。在这篇综合综述文章中,我们进行了文献检索,检索有关营养素及其缺乏与妇科疾病(即多囊卵巢综合征、不孕症、子宫肌瘤、子宫内膜异位症、痛经和感染,以及宫颈癌、子宫内膜癌和卵巢癌)之间的关系的信息。此外,我们还讨论了有前景的天然化合物和膳食补充剂对减轻这些重大疾病的潜在有益影响。
Diet and nutrition are fundamental in maintaining the general health of populations, including women’s health. Health status can be affected by nutrient deficiency and vice versa. Gene–nutrient interactions are important contributors to health management and disease prevention. Nutrition can alter gene expression, as well as the susceptibility to diseases, including cancer, through several mechanisms. Gynecological diseases in general are diseases involving the female reproductive system and include benign and malignant tumors, infections, and endocrine diseases. Benign diseases such as uterine fibroids and endometriosis are common, with a negative impact on women’s quality of life, while malignant tumors are among the most common cause of death in the recent years. In this comprehensive review article, a bibliographic search was performed for retrieving information about nutrients and how their deficiencies can be associated with gynecological diseases, namely polycystic ovary syndrome, infertility, uterine fibroids, endometriosis, dysmenorrhea, and infections, as well as cervical, endometrial, and ovarian cancers. Moreover, we discussed the potential beneficial impact of promising natural compounds and dietary supplements on alleviating these significant diseases.
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