MEDUSA: A cloud-based tool for the analysis of X-ray diffuse scattering to obtain the bending modulus from oriented membrane stacks.
MEDUSA: A cloud-based tool for the analysis of X-ray diffuse scattering to obtain the bending modulus from oriented membrane stacks.
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DOI:
10.1371/journal.pcbi.1011749
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发表时间:
2024-01
影响因子:
4.3
通讯作者:
中科院分区:
文献类型:
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An important mechanical property of cells is their membrane bending modulus, κ. Here, we introduce MEDUSA (MEmbrane DiffUse Scattering Analysis), a cloud-based analysis tool to determine the bending modulus, κ, from the analysis of X-ray diffuse scattering. MEDUSA uses GPU (graphics processing unit) accelerated hardware and a parallelized algorithm to run the calculations efficiently in a few seconds. MEDUSA’s graphical user interface allows the user to upload 2-dimensional data collected from different sources, perform background subtraction and distortion corrections, select regions of interest, run the fitting procedure and output the fitted parameters, the membranes’ bending modulus κ, and compressional modulus B.
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影响因子:
4
作者:
Himbert, Sebastian;Rheinstadter, Maikel C.
通讯作者:
Rheinstadter, Maikel C.
影响因子:
4.1
作者:
Himbert, Sebastian;Blacker, Matthew J.;Rheinstadter, Maikel C.
通讯作者:
Rheinstadter, Maikel C.
影响因子:
4.6
作者:
Himbert, Sebastian;Alsop, Richard J.;Rheinstadter, Maikel C.
通讯作者:
Rheinstadter, Maikel C.
影响因子:
2.4
作者:
Kucerka, N;Tristram-Nagle, S;Nagle, JF
通讯作者:
Nagle, JF
影响因子:
3.7
作者:
Himbert S;Gastaldo IP;Ahmed R;Pomier KM;Cowbrough B;Jahagirdar D;Ros S;Juhasz J;Stöver HDH;Ortega J;Melacini G;Bowdish DME;Rheinstädter MC
通讯作者:
Rheinstädter MC