Lymphatics in the liver.

Lymphatics in the liver.
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DOI:
10.1016/j.coi.2018.04.028
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发表时间:
2018-08
影响因子:
7
通讯作者:
Iwakiri Y
Iwakiri Y
中科院分区:
医学2区
文献类型:
--
作者:
Tanaka M;Iwakiri Y

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肝脏是最大的淋巴产生器官。在各种肝病中,包括但不限于肝硬化、病毒性肝炎和肝细胞癌,已经报道了肝淋巴管或淋巴管生成数量的显著增加。尽管如这些和其他观察所示,肝淋巴系统在健康和患病肝脏中具有明显的相关性,但对肝淋巴系统的研究很少。结合其他器官和组织中淋巴系统的知识,本文综述了肝淋巴系统的现有知识以及淋巴内皮细胞在肝脏健康和疾病中的潜在作用,并简要描述了肝淋巴系统研究的未来方向。
The liver is the largest lymph producing organ. A significant increase in the number of hepatic lymphatic vessels, or lymphangiogenesis, has been reported in various liver diseases, including, but not limited to, cirrhosis, viral hepatitis and hepatocellular carcinoma. Despite its apparent relevance in healthy and diseased livers as these and other observations indicate, the hepatic lymphatic system has been poorly studied. With knowledge of the lymphatic system in other organs and tissues incorporated, this review article addresses the current knowledge of the hepatic lymphatic system and the potential role of lymphatic endothelial cells in the health and the disease of the liver and concludes with a brief description on future directions of the study of the hepatic lymphatic system.
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