Representational similarity of social and valence information in the medial pFC.
Representational similarity of social and valence information in the medial pFC.
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DOI：
10.1162/jocn_a_00697
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发表时间：
2015-01
影响因子：
3.2
通讯作者：
Heatherton TF
中科院分区：
文献类型：
--
作者：
Chavez RS;Heatherton TF
人类的大脑非常擅长整合复杂的信息，形成对环境中的代理、对象和事件的统一的心理表征。这种能力特别突出的两个领域是社会和价信息的处理，并由内侧前额叶皮层（MPFC）的共同皮质区支持。因为社会信息通常嵌入在有价值的情感背景中，所以当同时呈现时，MPFC内的激活模式可能代表这两种认知过程。本研究采用大规模自动化元分析工具，结合多体素模式分析来研究功能性磁共振成像过程中MPFC中社会和价信息的表征相似性，从而验证了这种可能性。通过表征相似性分析，我们发现在MPFC的腹侧部分，在社会维度和价态维度内都存在高度的表征相似性，但在它们之间却没有（例如，积极的社会信息与消极的非社会信息高度不同）。这些结果与行为测量的相同刺激的相似性结构显著相关，表明社会和价信息的心理上有意义的表征是由腹侧MPFC的多体素激活模式反映的。
The human brain is remarkably adept at integrating complex information to form unified psychological representations of agents, objects, and events in the environment. Two domains in which this ability is particularly salient are the processing of social and valence information and are supported by common cortical areas in the medial prefrontal cortex (MPFC). Because social information is often embedded within valenced emotional contexts, it is possible that activation patterns within the MPFC may represent both of these types of cognitive processes when presented simultaneously. The current study tested this possibility by employing a large-scale automated meta-analysis tool, together with multi-voxel pattern analysis to investigate the representational similarity of social and valence information in the MPFC during functional magnetic resonance imaging. Using a representational similarity analysis, we found a high degree of representational similarity both within social dimensions and within valence dimensions, but not across them (e.g., positive social information was highly dissimilar to negative non-social information), in a ventral portion of the MPFC. These results were significantly correlated with a behaviorally measured similarity structure of the same stimuli, suggesting that a psychologically meaningful representation of social and valence information is reflected by multi-voxel activation patterns in the ventral MPFC.
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影响因子：
19.9
作者：
Etkin, Amit;Egner, Tobias;Kalisch, Raffael
通讯作者：
Kalisch, Raffael
影响因子：
4.2
作者：
Cunningham, William A.;Kirkland, Tabitha
通讯作者：
Kirkland, Tabitha
DOI：
10.1523/jneurosci.2335-09.2009
发表时间：
2009-09-16
期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子：
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作者：
Kim MJ;Whalen PJ
通讯作者：
Whalen PJ
DOI：
10.1073/pnas.0912838107
发表时间：
2010-03-30
影响因子：
11.1
作者：
Kahnt, Thorsten;Heinzle, Jakob;Haynes, John-Dylan
通讯作者：
Haynes, John-Dylan
DOI：
10.1523/jneurosci.2180-10.2010
发表时间：
2010-10-13
期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子：
--
作者：
Krienen FM;Tu PC;Buckner RL
通讯作者：
Buckner RL