The public health and clinical significance of Giardia and Cryptosporidium in domestic animals.
The public health and clinical significance of Giardia and Cryptosporidium in domestic animals.
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DOI：
10.1016/j.tvjl.2007.09.022
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发表时间：
2008-07
期刊：
影响因子：
--
通讯作者：
O'Handley R
中科院分区：
文献类型：
--
作者：
Thompson RC;Palmer CS;O'Handley R
贾第虫和隐孢子虫是家畜，特别是狗、猫和牲畜的常见肠道寄生虫。从临床和公共卫生的角度来看，它们的发生具有潜在的意义，但直到最近，对这些生物体的分类的混乱阻碍了对贾第虫和隐孢子虫感染的流行病学的清晰理解。最近应用分子流行病学工具有助于解决分类问题，从而确定传播周期。此外，在阐明与发病机制相关的机制方面取得了进展，而在化疗和预防领域仅取得了有限的进展。
Giardia and Cryptosporidium are common enteric parasites of domestic animals, particularly dogs, cats and livestock. Their occurrence is of potential significance from both clinical and public health perspectives yet, until recently, confusion over the taxonomy of these organisms prevented a clear understanding of the epidemiology of infections with both Giardia and Cryptosporidium. The recent application of molecular epidemiological tools has helped to resolve taxonomic issues, allowing cycles of transmission to be determined. In addition, advances have been made in elucidating mechanisms associated with pathogenesis, whereas only limited progress has been achieved in the areas of chemotherapy and prophylaxis.
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