Recent Development to Explore the Use of Biodegradable Periodic Mesoporous Organosilica (BPMO) Nanomaterials for Cancer Therapy.

Recent Development to Explore the Use of Biodegradable Periodic Mesoporous Organosilica (BPMO) Nanomaterials for Cancer Therapy.
复制标题

DOI:
10.3390/pharmaceutics12090890
复制
发表时间:
2020-09-18
期刊:
影响因子:
5.4
通讯作者:
Tamanoi F
Tamanoi F
中科院分区:
医学2区
文献类型:
--
作者:
Chinnathambi S;Tamanoi F

文献摘要

参考文献

被引文献

相似文献

多孔纳米材料可用于有效地装载各种抗癌药物,并以最小的毒性将其递送到体内的特定位置。可生物降解的周期性介孔有机硅纳米颗粒(BPMO)最近成为疾病靶向和药物递送的有希望的候选者。它们具有大的功能表面和具有可生物降解的有机基团框架的良好限定的孔。已经探索了多种生物降解方法,例如使用氧化还原、pH、酶活性和光。已经开发了使用BPMO的各种药物递送系统。本文综述了近年来BPMO在生物医学领域的应用进展。
Porous nanomaterials can be used to load various anti-cancer drugs efficiently and deliver them to a particular location in the body with minimal toxicity. Biodegradable periodic mesoporous organosilica nanoparticles (BPMOs) have recently emerged as promising candidates for disease targeting and drug delivery. They have a large functional surface and well-defined pores with a biodegradable organic group framework. Multiple biodegradation methods have been explored, such as the use of redox, pH, enzymatic activity, and light. Various drug delivery systems using BPMO have been developed. This review describes recent advances in the biomedical application of BPMOs.
DOI: 10.1002/adma.201401931
发表时间: 2014-09-17
期刊: ADVANCED MATERIALS
影响因子: 29.4
作者:
Croissant, Jonas;Cattoen, Xavier;Durand, Jean-Olivier
通讯作者: Durand, Jean-Olivier
DOI: 10.1039/c6tb01915c
发表时间: 2016-01-01
影响因子: 7
作者:
Jimenez, Chiara Mauriello;Knezevic, Nikola Z.;Durand, Jean-Olivier
通讯作者: Durand, Jean-Olivier
DOI: 10.1038/srep00534
发表时间: 2012
期刊: SCIENTIFIC REPORTS
影响因子: 4.6
作者:
Chinnathambi, Shanmugavel;Chen, Song;Ganesan, Singaravelu;Hanagata, Nobutaka
通讯作者: Hanagata, Nobutaka
DOI: 10.1038/359710a0
发表时间: 1992-10-22
期刊: NATURE
影响因子: 64.8
作者:
KRESGE, CT;LEONOWICZ, ME;BECK, JS
通讯作者: BECK, JS
DOI: 10.1038/47229
发表时间: 1999-12-23
期刊: NATURE
影响因子: 64.8
作者:
Asefa, T;MacLachlan, MJ;Ozin, GA
通讯作者: Ozin, GA