Stability of SARS-CoV-2 on critical personal protective equipment.
Stability of SARS-CoV-2 on critical personal protective equipment.
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DOI：
10.1038/s41598-020-80098-3
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发表时间：
2021-01-13
影响因子：
4.6
通讯作者：
Cutts T
中科院分区：
文献类型：
--
作者：
Kasloff SB;Leung A;Strong JE;Funk D;Cutts T
COVID-19在卫生保健环境中的传播令人担忧，卫生保健工作者在确诊病例中所占比例过高。虽然已经发现SARS-CoV-2病毒在物体表面持续存在数天，但污染物作为一种传播方式的范围和持续时间，特别是在卫生保健环境中，尚未得到充分的描述。为了阐明这一关键问题，本研究首次全面评估了SARS-CoV-2在卫生工作者和公众广泛使用的被实验污染的个人防护装备（PPE）上的稳定性。在八种不同的材料上监测了活病毒在21天内的持久性，包括丁腈医学检查手套、增强耐化学手套、N-95和N-100颗粒呼吸器口罩、特卫强、塑料、棉花和不锈钢。与以前的报告不同，在土壤负荷存在的情况下，活性SARS-CoV-2在实验接种的个人防护装备上持续存在长达21天，包括过滤式口罩（N-95和N-100口罩）和塑料遮阳板的材料。相反，当应用于100%纯棉织物时，病毒迅速降解，并在24小时内无法通过TCID50检测到。这些发现强调了在高风险环境中使用期间和之后适当处理受污染的个人防护用品的重要性，并为棉花在限制COVID-19传播方面的潜在效用提供了有趣的见解。
The spread of COVID-19 in healthcare settings is concerning, with healthcare workers representing a disproportionately high percentage of confirmed cases. Although SARS-CoV-2 virus has been found to persist on surfaces for a number of days, the extent and duration of fomites as a mode of transmission, particularly in healthcare settings, has not been fully characterized. To shed light on this critical matter, the present study provides the first comprehensive assessment of SARS-CoV-2 stability on experimentally contaminated personal protective equipment (PPE) widely used by healthcare workers and the general public. Persistence of viable virus was monitored over 21 days on eight different materials, including nitrile medical examination gloves, reinforced chemical resistant gloves, N-95 and N-100 particulate respirator masks, Tyvek, plastic, cotton, and stainless steel. Unlike previous reports, viable SARS-CoV-2 in the presence of a soil load persisted for up to 21 days on experimentally inoculated PPE, including materials from filtering facepiece respirators (N-95 and N-100 masks) and a plastic visor. Conversely, when applied to 100% cotton fabric, the virus underwent rapid degradation and became undetectable by TCID50 assay within 24 h. These findings underline the importance of appropriate handling of contaminated PPE during and following use in high-risk settings and provide interesting insight into the potential utility of cotton in limiting COVID-19 transmission.
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影响因子：
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作者：
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通讯作者：
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通讯作者：
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使用7种广泛可用的灭菌方法的N95口罩进行净化。
影响因子：
3.7
作者：
Kumar A;Kasloff SB;Leung A;Cutts T;Strong JE;Hills K;Gu FX;Chen P;Vazquez-Grande G;Rush B;Lother S;Malo K;Zarychanski R;Krishnan J
通讯作者：
Krishnan J