Executive functioning at ages 5 and 7 years in children with prenatal cocaine exposure.
Executive functioning at ages 5 and 7 years in children with prenatal cocaine exposure.
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DOI：
10.1159/000207500
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发表时间：
2009
影响因子：
2.9
通讯作者：
Garvan CW
中科院分区：
文献类型：
--
作者：
Eyler FD;Warner TD;Behnke M;Hou W;Wobie K;Garvan CW
本前瞻性纵向研究评估了产前可卡因暴露（PCE）对5岁和7岁儿童执行功能的影响。通过尿液毒理学和结构化访谈确定的154名怀孕可卡因使用者与154名非使用者相匹配。儿童由经过认证的蒙面评估员进行评估，护理人员在家访期间由经验丰富的工作人员进行访谈。在大约90%的5岁和7岁的幸存样本中，结构方程模型表明，出生时头围的增加（经妊娠调整）显著预示着执行功能的更好表现，并且PCE通过其对出生时头围的显着负面影响间接与执行功能相关。在5岁时，环境质量也能预测执行功能，总模型的R2为0.24。7岁时，照顾者功能预测环境质量，环境质量反过来与执行功能正相关，女孩的执行功能更好。7岁时的总模型占执行功能方差的30%。
This prospective longitudinal study evaluated the effect of prenatal cocaine exposure (PCE) on executive functioning in 5- and 7-year-old children. In total, 154 pregnant cocaine users, identified by urine toxicology and structured interviews, were matched to 154 nonusers. Children were assessed by certified masked evaluators, and caregivers were interviewed by experienced staff during home visits. In approximately 90% of the surviving sample tested at ages 5 and 7 years, structural equation modeling demonstrated that an increased head circumference at birth (adjusted for gestation) significantly predicted better performance on executive functioning, and that PCE was indirectly related to executive functioning through its significant negative effect on head circumference at birth. At age 5 years, quality of environment also predicted executive functioning, and the R2 for the total model was 0.24. At 7 years, caregiver functioning predicted quality of environment, which in turn was positively related to executive functioning, and girls had better executive functioning. The total model at age 7 years accounted for 30% of the variance in executive functioning.
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DOI：
10.1017/s1121189x00002001
发表时间：
2006-01-01
期刊：
EPIDEMIOLOGIA E PSICHIATRIA SOCIALE
影响因子：
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作者：
Accornero, VH;Anthony, JC;Bandstra, ES
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DOI：
10.1097/00004703-200404000-00002
发表时间：
2004-04-01
影响因子：
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作者：
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通讯作者：
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DOI：
10.1097/00004703-199912000-00003
发表时间：
1999-12-01
影响因子：
2.4
作者：
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通讯作者：
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影响因子：
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作者：
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