Current concepts in the pathophysiology of glaucoma.

Current concepts in the pathophysiology of glaucoma.
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DOI:
10.4103/0301-4738.53049
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发表时间:
2009-07
影响因子:
3.1
通讯作者:
Agrawal SS
Agrawal SS
中科院分区:
医学4区
文献类型:
--
作者:
Agarwal R;Gupta SK;Agarwal P;Saxena R;Agrawal SS

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Glaucoma, the second leading cause of blindness, is characterized by changes in the optic disc and visual field defects. The elevated intraocular pressure was considered the prime factor responsible for the glaucomatous optic neuropathy involving death of retinal ganglion cells and their axons. Extensive investigations into the pathophysiology of glaucoma now reveal the role of multiple factors in the development of retinal ganglion cell death. A better understanding of the pathophysiological mechanisms involved in the onset and progression of glaucomatous optic neuropathy is crucial in the development of better therapeutic options. This review is an effort to summarize the current concepts in the pathophysiology of glaucoma so that newer therapeutic targets can be recognized. The literature available in the National Medical Library and online Pubmed search engine was used for literature review.
DOI: 10.1007/bf00946939
发表时间: 1997-10-01
影响因子: 2.7
作者:
Gass, A;Flammer, J;Haefeli, WE
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