Antimicrobial hydrogels for the treatment of infection.

Antimicrobial hydrogels for the treatment of infection.
复制标题

DOI:
10.1002/bip.22412
复制
发表时间:
2013-11
期刊:
影响因子:
2.9
通讯作者:
Schneider, Joel P.
Schneider, Joel P.
中科院分区:
生物学4区
文献类型:
--
作者:
Veiga, Ana Salome;Schneider, Joel P.

文献摘要

参考文献

被引文献

相似文献

微生物感染,特别是与受损的伤口愈合和生物医学植入物失效相关的微生物感染的日益普遍,刺激了具有抗微生物活性的新材料的开发。水凝胶是一类高度水合的材料,可用于多种医学应用,例如药物递送、组织工程、作为伤口填充物和作为植入物涂层等。许多凝胶的生物相容性使其成为开发选择性活性抗微生物材料的方便起始平台。具有抗微生物性质的水凝胶可以通过已知抗微生物剂的包封或共价固定来获得,或者材料本身可以被设计为具有固有的抗微生物活性。在这篇综述中,我们提出了一个概述,最近开发的抗菌水凝胶,并在可能的情况下,提供了讨论有关其作用机制。
The increasing prevalence of microbial infections, especially those associated with impaired wound healing and biomedical implant failure has spurred the development of new materials having antimicrobial activity. Hydrogels are a class of highly hydrated material finding use in diverse medical applications such as drug delivery, tissue engineering, as wound fillers and as implant coatings, to name a few. The biocompatible nature of many gels make them a convenient starting platform to develop selectively active antimicrobial materials. Hydrogels with antimicrobial properties can be obtained through the encapsulation or covalent immobilization of known antimicrobial agents, or the material itself can be designed to possess inherent antimicrobial activity. In this review we present an overview of antimicrobial hydrogels that have recently been developed and when possible provide a discussion relevant to their mechanism of action.
DOI: 10.1586/eri.11.59
发表时间: 2011-07
影响因子: 5.7
作者:
Dai T;Tanaka M;Huang YY;Hamblin MR
通讯作者: Hamblin MR
DOI: 10.1128/aac.05463-11
发表时间: 2012-01-01
影响因子: 4.9
作者:
Aziz, Manal A.;Cabral, Jaydee D.;Hanton, Lyall R.
通讯作者: Hanton, Lyall R.
DOI: 10.1016/j.biomaterials.2009.11.016
发表时间: 2010-02
期刊: BIOMATERIALS
影响因子: 14
作者:
Hudson, Sarah P.;Langer, Robert;Fink, Gerald R.;Kohane, Daniel S.
通讯作者: Kohane, Daniel S.
DOI: 10.1016/j.biomaterials.2012.02.027
发表时间: 2012-05
期刊: BIOMATERIALS
影响因子: 14
作者:
Fullenkamp, Dominic E.;Rivera, Jose G.;Gong, Yong-kuan;Lau, K. H. Aaron;He, Lihong;Varshney, Rahul;Messersmith, Phillip B.
通讯作者: Messersmith, Phillip B.
DOI: 10.1007/s10856-009-3795-0
发表时间: 2009-11-01
影响因子: 3.7
作者:
Halpenny, Genevieve M.;Steinhardt, Rachel C.;Mascharak, Pradip K.
通讯作者: Mascharak, Pradip K.