Discounting of delayed rewards and executive dysfunction in individuals infected with hepatitis C.
Discounting of delayed rewards and executive dysfunction in individuals infected with hepatitis C.
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DOI：
10.1080/13803395.2010.499355
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发表时间：
2011-02
影响因子：
2.2
通讯作者：
Hoffman W
中科院分区：
文献类型：
--
作者：
Huckans M;Seelye A;Woodhouse J;Parcel T;Mull L;Schwartz D;Mitchell A;Lahna D;Johnson A;Loftis J;Woods SP;Mitchell SH;Hoffman W
确定丙型肝炎成年人，无论物质使用障碍如何，是否比没有丙型肝炎的成年人更有可能贴现延迟奖励，并探索延迟贴现与神经心理功能之间的关系。程序包括临床访谈，神经心理学测试和延迟折扣任务。无论药物滥用史如何，患有丙型肝炎的成年人更有可能选择较小的即时奖励而不是较大的延迟奖励。延迟折扣与执行功能任务的表现相关。折扣的增加与广泛的执行功能障碍有关，这表明HCV相关的执行功能障碍可能会导致决策风格的改变。
Determine whether adults with hepatitis C, regardless of substance use disorder, are more likely to discount delayed rewards than adults without hepatitis C, and explore the relationship between delay discounting and neuropsychological functioning. Procedures included clinical interviews, neuropsychological testing, and a delay discounting task. Regardless of substance abuse history, adults with hepatitis C were significantly more likely to choose smaller immediate rewards over larger delayed rewards. Delay discounting correlated with performance on executive functioning tasks. Increased discounting is associated with broad executive dysfunction, suggesting that HCV associated executive dysfunction may lead to altered decision making style.
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