The Origin of Reproductive Isolation: Biological Mechanisms of Genetic Incompatibility

The Origin of Reproductive Isolation: Biological Mechanisms of Genetic Incompatibility
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生殖隔离的起源:遗传不相容的生物学机制

DOI:
10.1007/978-4-431-65930-3_1
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发表时间:
2000
期刊:
影响因子:
2.5
通讯作者:
K. Sawamura
K. Sawamura
中科院分区:
生物学4区
文献类型:
--
作者:
K. Sawamura

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自查尔斯达尔文时代以来,物种的起源一直是神秘中的神秘。根据现代综合学派创始人所倡导的生物物种概念,“新物种如何进化”的问题可以被一个更容易回答的问题“种群之间如何建立生殖隔离”所取代。阻止物种间基因交换的机制多种多样,其中大多数被认为是遗传多样性的结果,而不是原因。一些干扰物种识别系统(前合子隔离),和其他终止世代的混合基因组(后合子隔离)。后者的生物学机制的例子最近被记录良好(肿瘤发生,性逆转,不规则的剂量补偿,核仁优势,同源异型转化,生精缺陷,有丝分裂缺陷,和种间杂种的母亲/合子转换失败)在这里进行审查。来自不同物种的基因座之间的相互作用起着重要的作用。正如发育生物学所示,转录调控可能是一个关键因素。杂交后代的遗传不亲和性可能是DNA结合蛋白及其结合位点共同进化导致转录调控不当的表现。
The origin of species has been the mystery of mysteries since Charles Darwin’s era. According to the biological species concept advocated by the founders of the Modern Synthesis, the question ‘how new species evolve’ can be substituted by a more answerable question ‘how reproductive isolation is established between populations’. Mechanisms preventing gene exchange between species are various, and most of them are thought to be the result, not the cause, of genetic diversity. Some disturb species recognition systems (prezygotic isolation), and others terminate generations of mixed genomes (postzygotic isolation). Examples of the latter whose biological mechanisms have recently been documented well (tumorigenesis, sexual reversion, irregular dosage compensation, nucleolar dominance, homeotic transformation, spermatogenic defects, mitotic defects, and maternal/zygotic transition failure in interspecific hybrids) are reviewed here. Gene interactions between loci from different species play important roles. As has been shown in developmental biology, transcriptional regulation may be a key factor. Genetic incompatibility in hybrids may be the manifestation of improper transcriptional regulation resulting from the coevolution of DNA-binding proteins and their binding sites.
通过将毛里求斯果蝇染色体的标记片段渗入模拟果蝇中,对杂交不相容因素进行全基因组调查。
DOI: 10.1093/genetics/142.3.819
发表时间: 1996
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影响因子: 3.3
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发表时间: 1998
期刊: Genetics
影响因子: 3.3
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DOI: 10.1016/0012-1606(91)90240-4
发表时间: 1991
影响因子: 2.7
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Taketo,T;Saeed,J;Nishioka,Y;Donahoe,PK
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DOI: 10.1002/bies.950080608
发表时间: 1988
期刊: BioEssays : news and reviews in molecular, cellular and developmental biology
影响因子: --
作者:
Dickinson,WJ
通讯作者: Dickinson,WJ