The ghosts of brain states past: remembering reactivates the brain regions engaged during encoding.
The ghosts of brain states past: remembering reactivates the brain regions engaged during encoding.
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DOI:
10.1037/a0017937
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发表时间:
2010-01
影响因子:
22.4
通讯作者:
Anderson, John R.
中科院分区:
文献类型:
--
作者:
Danker, Jared F.;Anderson, John R.
There is growing evidence that the brain regions involved in encoding an episode are partially reactivated when that episode is later remembered. That is, the process of remembering an episode involves literally returning to the brain state that was present during that episode. This paper reviews studies of episodic and associative memory that provide support for the assertion that encoding regions are reactivated during subsequent retrieval. In the first section, studies are reviewed in which neutral stimuli are associated with different modalities of sensory stimuli or different valences of emotional stimuli. When the neutral stimuli are later used as retrieval cues, relevant sensory and emotion processing regions are reactivated. In the second section, studies are reviewed in which participants employ different strategies for encoding stimuli. When the stimuli are later retrieved, regions associated with the different encoding strategies are reactivated. Together, these studies demonstrate not only that the encoding experience determines which regions are activated during subsequent retrieval, but also that the same regions are activated during encoding and retrieval. In the final section, relevant questions are posed and discussed regarding the reactivation of encoding regions during retrieval.
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