The mismatch negativity: a review of underlying mechanisms.

The mismatch negativity: a review of underlying mechanisms.
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DOI:
10.1016/j.clinph.2008.11.029
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发表时间:
2009-03
期刊:
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
影响因子:
--
通讯作者:
Friston KJ
Friston KJ
中科院分区:
其他
文献类型:
--
作者:
Garrido MI;Kilner JM;Stephan KE;Friston KJ

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失配负波(MMN)是大脑对违反规则的反应,由一系列感官刺激(通常在听觉域)建立[Näätänen R.注意力和大脑功能。希尔斯代尔,NJ:Lawrence Erlbaum; 1992]。MMN反映了大脑在连续刺激之间进行自动比较的能力,并提供了感觉学习和感知准确性的电生理指标。虽然MMN已被广泛研究,但MMN的神经生理机制还不清楚。人们提出了几种假说来解释MMN的产生,其中,“适应假说”和“模型调整假说”受到了最多的关注。本文提出了一个审查的研究,重点关注的神经元机制的MMN生成,讨论了两个主要的解释性假设,并提出预测编码作为一个一般的框架,试图统一两者。
The mismatch negativity (MMN) is a brain response to violations of a rule, established by a sequence of sensory stimuli (typically in the auditory domain) [Näätänen R. Attention and brain function. Hillsdale, NJ: Lawrence Erlbaum; 1992]. The MMN reflects the brain’s ability to perform automatic comparisons between consecutive stimuli and provides an electrophysiological index of sensory learning and perceptual accuracy. Although the MMN has been studied extensively, the neurophysiological mechanisms underlying the MMN are not well understood. Several hypotheses have been put forward to explain the generation of the MMN; amongst these accounts, the “adaptation hypothesis” and the “model adjustment hypothesis” have received the most attention. This paper presents a review of studies that focus on neuronal mechanisms underlying the MMN generation, discusses the two major explanatory hypotheses, and proposes predictive coding as a general framework that attempts to unify both.
DOI: 10.1101/lm.46502
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