Information-motivation-behavioral skills barriers associated with intentional versus unintentional ARV non-adherence behavior among HIV+ patients in clinical care.
Information-motivation-behavioral skills barriers associated with intentional versus unintentional ARV non-adherence behavior among HIV+ patients in clinical care.
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DOI：
10.1080/09540121003758630
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发表时间：
2010-08
期刊：
影响因子：
1.7
通讯作者：
Fisher JD
中科院分区：
文献类型：
--
作者：
Norton WE;Amico KR;Fisher WA;Shuper PA;Ferrer RA;Cornman DH;Trayling CA;Redding C;Fisher JD
自抗逆转录病毒(ARV)疗法问世以来，艾滋病毒已变得更好地被描述为一种慢性病，而不是绝症，部分取决于一个人保持相对较高水平的坚持的能力。尽管有关于抗逆转录病毒药物依从性行为障碍和促进剂的研究，但人们对艾滋病毒阳性者所面临的具体挑战知之甚少，这些人报告说“休息”了他们的抗逆转录病毒药物。这项研究使用了ARV依从性的信息-动机-行为技能模型作为一个框架，以了解与依从性相关的障碍，这些障碍可能会区分报告“休息”的非依从性患者和那些没有报告“休息”他们的ARV药物的患者。327名HIV阳性患者的样本提供了这项研究的数据，这些患者报告的依从性在研究基线时低于100%。那些报告在没有事先与医疗保健提供者交谈的情况下停止服用艾滋病毒药物的参与者被归类为故意不遵守规定，而那些没有在事先与医疗保健提供者交谈的情况下报告“休息”的参与者被归类为无意不遵守规定。分析检查了有意和无意的非依从性患者在人口统计学特征和对依从性相关信息、动机和行为技能问卷项目的反应方面的差异。在人口统计学、坚持相关信息或坚持相关动机上，两组之间几乎没有差异；然而，在大约一半与坚持相关的行为技能项目上，观察到了显著差异。对未来研究的启示，以及特定干预组件的设计，以减少故意不遵守的行为，进行了讨论。
Since the arrival of antiretroviral (ARV) therapy, HIV has become better characterized as a chronic disease rather than a terminal illness, depending in part on one’s ability to maintain relatively high levels of adherence. Despite research concerning barriers and facilitators of ARV adherence behavior, relatively little is known about specific challenges faced by HIV-positive persons who report “taking a break” from their ARV medications. The present study employed the Information-Motivation-Behavioral Skills Model of ARV Adherence as a framework for understanding adherence-related barriers that may differentiate between non-adherent patients who report “taking a break” versus those who do not report “taking a break” from their ARV medications. A sample of 327 HIV-positive patients who reported less than 100% adherence at study baseline provided data for this research. Participants who reported “taking a break” from their HIV medications without first talking to their healthcare provider were classified as intentionally non-adherent, while those who did not report “taking a break” without first talking with their healthcare provider were classified as unintentionally non-adherent. Analyses examined differences between intentionally versus unintentionally non-adherent patients with respect to demographic characteristics and responses to the adherence-related information, motivation, and behavioral skills questionnaire items. Few differences were observed between the groups on demographics, adherence-related information or adherence-related motivation; however, significant differences were observed on about half of the adherence-related behavioral skills items. Implications for future research, as well as the design of specific intervention components to reduce intentionally non-adherent behavior, are discussed.
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影响因子：
4.4
作者：
Amico, K. Rivet;Barta, William;Fisher, William A.
通讯作者：
Fisher, William A.
DOI：
10.1080/09540120500038058
发表时间：
2005-08-01
影响因子：
1.7
作者：
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通讯作者：
Fisher, JD
影响因子：
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作者：
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通讯作者：
Fallowfield, Lesley
影响因子：
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作者：
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通讯作者：
Bangsberg, DR
影响因子：
11.4
作者：
Chen, Luke F.;Hoy, Jennifer;Lewin, Sharon R.
通讯作者：
Lewin, Sharon R.