High-frequency ultrasound m-mode imaging for identifying lesion and bubble activity during high-intensity focused ultrasound ablation.
High-frequency ultrasound m-mode imaging for identifying lesion and bubble activity during high-intensity focused ultrasound ablation.
复制标题
DOI：
10.1016/j.ultrasmedbio.2012.01.004
复制
发表时间：
2012-04
影响因子：
2.9
通讯作者：
Deng, Cheri X.
中科院分区：
文献类型：
--
作者：
Kumon, Ronald E.;Gudur, Madhu S. R.;Zhou, Yun;Deng, Cheri X.
关键词：
高强度聚焦超声(HIFU)消融过程的有效实时监测对于HIFU技术在介入性电生理中的应用具有重要意义。这项研究探讨了快速、高频M型超声成像用于监测HIFU应用过程中的时空变化。采用同焦垂直排列高频成像系统(Visualsonics Vevo 770，中心频率55 MHz)，对体外培养的猪心脏组织标本进行高强度聚焦超声(4.33 MHz，1 kHzPRF，50%占空比，1 S，2600~6100W/cm2)。分别于治疗前、治疗中和治疗后(n=12)采集M型超声心动图(1 kHzPRF，2 S×7 mm)的射频数据。在几种方法中，阈值变化+12分贝的时间最大背向散射积分对最终病灶宽度的识别效果最好(受试者-工作特征曲线面积0.91±0.04，准确率85±8%，与肉眼图像相比)。提出了一种基于线-线去相关系数的瞬变气体识别判据。
Effective real-time monitoring of high-intensity focused ultrasound (HIFU) ablation is important for application of HIFU technology in interventional electrophysiology. This study investigated rapid, high-frequency M-mode ultrasound imaging for monitoring spatiotemporal changes during HIFU application. HIFU (4.33 MHz, 1 kHz PRF, 50% duty cycle, 1 s, 2600 – 6100 W/cm2) was applied to ex-vivo porcine cardiac tissue specimens with a confocally and perpendicularly aligned high-frequency imaging system (Visualsonics Vevo 770, 55 MHz center frequency). Radiofrequency (RF) data from M-mode imaging (1 kHz PRF, 2 s × 7 mm) was acquired before, during, and after HIFU treatment (n = 12). Among several strategies, the temporal maximum integrated backscatter with a threshold of +12 dB change showed the best results for identifying final lesion width (receiver-operating characteristic curve area 0.91 ± 0.04, accuracy 85 ± 8%, as compared to macroscopic images of lesions). A criterion based on a line-to-line decorrelation coefficient is proposed for identification of transient gas bodies.
登录
查看更多内容
影响因子：
4.6
作者：
Farny, Caleb H.;Holt, R. Glynn;Roy, Ronald A.
通讯作者：
Roy, Ronald A.
影响因子：
8.8
作者：
通讯作者：
--
影响因子：
2.9
作者：
Abe, Yukio;Otsuka, Ryo;Homma, Shunichi
通讯作者：
Homma, Shunichi
DOI：
10.1121/1.1559911
发表时间：
2003-04-01
期刊：
ACOUSTICS RESEARCH LETTERS ONLINE-ARLO
影响因子：
--
作者：
Chen, WS;Lafon, C;Crum, LA
通讯作者：
Crum, LA
影响因子：
2.4
作者：
DAMIANOU, C;HYNYNEN, K
通讯作者：
HYNYNEN, K