Generic acquisition protocol for quantitative MRI of the spinal cord.

Generic acquisition protocol for quantitative MRI of the spinal cord.
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DOI:
10.1038/s41596-021-00588-0
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发表时间:
2021-10
期刊:
影响因子:
14.8
通讯作者:
Xu J
Xu J
中科院分区:
生物学1区
文献类型:
--
作者:
Cohen-Adad J;Alonso-Ortiz E;Abramovic M;Arneitz C;Atcheson N;Barlow L;Barry RL;Barth M;Battiston M;Büchel C;Budde M;Callot V;Combes AJE;De Leener B;Descoteaux M;de Sousa PL;Dostál M;Doyon J;Dvorak A;Eippert F;Epperson KR;Epperson KS;Freund P;Finsterbusch J;Foias A;Fratini M;Fukunaga I;Wheeler-Kingshott CAMG;Germani G;Gilbert G;Giove F;Gros C;Grussu F;Hagiwara A;Henry PG;Horák T;Hori M;Joers J;Kamiya K;Karbasforoushan H;Keřkovský M;Khatibi A;Kim JW;Kinany N;Kitzler H;Kolind S;Kong Y;Kudlička P;Kuntke P;Kurniawan ND;Kusmia S;Labounek R;Laganà MM;Laule C;Law CS;Lenglet C;Leutritz T;Liu Y;Llufriu S;Mackey S;Martinez-Heras E;Mattera L;Nestrasil I;O'Grady KP;Papinutto N;Papp D;Pareto D;Parrish TB;Pichiecchio A;Prados F;Rovira À;Ruitenberg MJ;Samson RS;Savini G;Seif M;Seifert AC;Smith AK;Smith SA;Smith ZA;Solana E;Suzuki Y;Tackley G;Tinnermann A;Valošek J;Van De Ville D;Yiannakas MC;Weber KA 2nd;Weiskopf N;Wise RG;Wyss PO;Xu J

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定量脊髓(SC)磁共振成像(MRI)提出了许多挑战,包括缺乏标准化的成像方案。在这里,我们为来自三家主要制造商:GE、飞利浦和西门子的3T MRI系统的用户提供了一种前瞻性协调的定量MRI协议,我们称之为脊柱通用协议。该方案为评估SC的宏观和微观结构完整性提供了指导:用于SC横截面积(CSA)计算的T1加权和T2加权成像,用于灰质CSA的多回波梯度回波,以及用于评估白质微观结构的磁化传递和扩散加权成像。在同一作者的一篇配对论文中,使用了脊柱通用协议来获取260名健康受试者的42个中心的数据。脊柱通用协议的关键细节也可以在开放获取的文档中找到,该文档可以在以下网址找到:https://spinalcordmri.org/protocols.该方案将作为研究人员和临床医生实施新的SC成像计划的起点,以便在未来将SC包括在神经成像协议中将更加普遍。该方案可由任何训练有素的MR技术人员或熟悉MRI采集的研究人员/临床医生实施。
Quantitative spinal cord (SC) magnetic resonance imaging (MRI) presents many challenges, including a lack of standardized imaging protocols. Here we present a prospectively harmonized quantitative MRI protocol, which we refer to as the spine generic protocol, for users of 3T MRI systems from the three main manufacturers: GE, Philips and Siemens. The protocol provides guidance for assessing SC macrostructural and microstructural integrity: T1-weighted and T2-weighted imaging for SC cross-sectional area (CSA) computation, multi-echo gradient echo for gray matter CSA, and magnetization transfer and diffusion weighted imaging for assessing white matter microstructure. In a companion paper from the same authors, the spine generic protocol was used to acquire data across 42 centers in 260 healthy subjects. The key details of the spine generic protocol are also available in an open-access document that can be found at: https://spinalcordmri.org/protocols. The protocol will serve as a starting point for researchers and clinicians implementing new SC imaging initiatives so that, in the future, inclusion of the SC in neuroimaging protocols will be more common. The protocol could be implemented by any trained MR technician or by a researcher/clinician familiar with MRI acquisition.
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