Insect Insights at the Single-Cell Level: Technologies and Applications.
Insect Insights at the Single-Cell Level: Technologies and Applications.
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单细胞技术是一种很有前途的方法，可以在细胞水平上揭示转录本的复杂性和异质性，并揭示组织或器官中不同细胞类型和功能的组成。近年来，单细胞RNA测序（scRNA-seq）的进展进一步改变了我们对生物系统的看法。scRNA-seq在昆虫中的应用能够全面表征常见和罕见的细胞类型和细胞状态，发现新的细胞类型，并揭示细胞类型之间的相互关系。最近scRNA-seq技术在昆虫组织中的应用带来了许多令人兴奋的发现。在这里，我们提供了scRNA-seq及其在昆虫研究中的应用的概述，重点是生物学应用，当前的挑战，以及未来的机会，使新的发现与scRNA-seq在昆虫。
Single-cell techniques are a promising way to unravel the complexity and heterogeneity of transcripts at the cellular level and to reveal the composition of different cell types and functions in a tissue or organ. In recent years, advances in single-cell RNA sequencing (scRNA-seq) have further changed our view of biological systems. The application of scRNA-seq in insects enables the comprehensive characterization of both common and rare cell types and cell states, the discovery of new cell types, and revealing how cell types relate to each other. The recent application of scRNA-seq techniques to insect tissues has led to a number of exciting discoveries. Here we provide an overview of scRNA-seq and its application in insect research, focusing on biological applications, current challenges, and future opportunities to make new discoveries with scRNA-seq in insects.
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影响因子：
64.5
作者：
Davie K;Janssens J;Koldere D;De Waegeneer M;Pech U;Kreft Ł;Aibar S;Makhzami S;Christiaens V;Bravo González-Blas C;Poovathingal S;Hulselmans G;Spanier KI;Moerman T;Vanspauwen B;Geurs S;Voet T;Lammertyn J;Thienpont B;Liu S;Konstantinides N;Fiers M;Verstreken P;Aerts S
通讯作者：
Aerts S
中肠细胞的异质性及其对蚊子艾德斯埃及摄入血餐的差异反应。
影响因子：
3.8
作者：
Cui Y;Franz AWE
通讯作者：
Franz AWE
单细胞染色质可及性揭示了调节变化的原理。
影响因子：
64.8
作者：
Buenrostro JD;Wu B;Litzenburger UM;Ruff D;Gonzales ML;Snyder MP;Chang HY;Greenleaf WJ
通讯作者：
Greenleaf WJ
影响因子：
3.6
作者：
Dillon, Noah;Cocanougher, Ben;Sood, Chhavi;Yuan, Xin;Kohn, Andrea B.;Moroz, Leonid L.;Siegrist, Sarah E.;Zlatic, Marta;Doe, Chris Q.
通讯作者：
Doe, Chris Q.
影响因子：
5.6
作者：
Tse, Joyce;Li, Tsz Ho;Zhang, Jizhou;Lee, Alan Chun Kit;Lee, Ivy;Qu, Zhe;Lin, Xiao;Hui, Jerome;Chan, Ting-Fung
通讯作者：
Chan, Ting-Fung