Inter-mosaic coordination of retinal receptive fields.

Inter-mosaic coordination of retinal receptive fields.
复制标题

DOI:
10.1038/s41586-021-03317-5
复制
发表时间:
2021-04
期刊:
影响因子:
64.8
通讯作者:
Field GD
Field GD
中科院分区:
综合性期刊1区
文献类型:
--
作者:
Roy S;Jun NY;Davis EL;Pearson J;Field GD

文献摘要

参考文献

相似文献

视网膜的输出被组织成许多检测器网格,称为“马赛克”,将视觉场景的不同特征信号传递给大脑。每个马赛克包含一个单一的视网膜神经节细胞(RGC)类型,其接受野(RFs)覆盖空间。许多马赛克是成对出现的,分别表示特定视觉特征的增量(ON)和递减(OFF)。利用高效编码模型,我们确定了如何排列这些拼接对以优化自然场景的编码。我们发现当这些马赛克对是反对齐时,信息是最大化的,这意味着马赛克之间的RF中心比偶然预期的距离要远。我们通过对大鼠和灵长类动物的RGC光响应进行大规模测量而获得的多个RF马赛克来验证这一预测。我们发现具有相似特征选择性的ON和OFF RGC对表现出反对准的RF马赛克,与理论一致。编码不同特征的ON和OFF类型表现出独立的马赛克。这些结果将有效编码理论(ECT)扩展到单个细胞之外,以预测不同RGC类型的种群如何在空间上排列。
The output of the retina is organized into many detector grids, called ‘mosaics’ that signal different features of visual scenes to the brain. Each mosaic comprises a single retinal ganglion cell (RGC) type, whose receptive fields (RFs) tile space. Many mosaics arise as pairs, signaling increments (ON) and decrements (OFF), respectively, of a particular visual feature. Using a model of efficient coding, we determine how such mosaic pairs should be arranged to optimize the encoding of natural scenes. We find that information is maximized when these mosaic pairs are anti-aligned, meaning the RF centers between mosaics are more distant than expected by chance. We test this prediction across multiple RF mosaics acquired with large-scale measurements of RGC light responses from rat and primate. We find that ON and OFF RGC pairs with similar feature selectivity exhibit anti-aligned RF mosaics, consistent with theory. ON and OFF types that encode distinct features exhibit independent mosaics. These results extend efficient coding theory (ECT) beyond individual cells to predict how populations of diverse RGC types are spatially arranged.
DOI: 10.1046/j.1460-9568.1999.00555.x
发表时间: 1999-04-01
影响因子: 3.4
作者:
Galli-Resta, L;Novelli, E;Reese, BE
通讯作者: Reese, BE
DOI: 10.1523/jneurosci.4036-12.2012
发表时间: 2012-11-14
期刊: The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子: --
作者:
Doi E;Gauthier JL;Field GD;Shlens J;Sher A;Greschner M;Machado TA;Jepson LH;Mathieson K;Gunning DE;Litke AM;Paninski L;Chichilnisky EJ;Simoncelli EP
通讯作者: Simoncelli EP
DOI: 10.1152/jn.1997.78.4.2048
发表时间: 1997-10-01
影响因子: 2.5
作者:
DeVries, SH;Baylor, DA
通讯作者: Baylor, DA
DOI: 10.1016/j.cell.2018.04.040
发表时间: 2018-05-17
期刊: CELL
影响因子: 64.5
作者:
Bae, J. Alexander;Mu, Shang;Seung, H. Sebastian
通讯作者: Seung, H. Sebastian
DOI: 10.1017/s0952523805226147
发表时间: 2005-11-01
影响因子: 1.9
作者:
Eglen, SJ;Diggle, PJ;Troy, JB
通讯作者: Troy, JB