Neural congruency effects in the multi-source interference task vanish in healthy youth after controlling for conditional differences in mean RT.
Neural congruency effects in the multi-source interference task vanish in healthy youth after controlling for conditional differences in mean RT.
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DOI：
10.1371/journal.pone.0060710
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发表时间：
2013
期刊：
影响因子：
3.7
通讯作者：
Weissman DH
中科院分区：
文献类型：
--
作者：
Kim K;Carp J;Fitzgerald KD;Taylor SF;Weissman DH
根据认知控制的冲突监测模型，干扰物干扰任务（如Stroop任务）中的反应时间是比刺激一致性（不一致vs一致）更精确的反应冲突指标。因此，该模型预测，RT应该是检测反应冲突的后内侧额叶皮质（pMFC）区域活动的可靠预测器。特别是，在给定的任务条件下（例如，一致），慢速rt试验中的pMFC活动应该大于快速rt试验，(b)在不同条件下的rt匹配试验中（即，一致和不一致试验）相等。这两种影响已经在成人的功能性磁共振成像（MRI）研究中观察到。然而，在最近的一项健康青年研究中没有观察到这两种影响，这表明(a)该模型不能准确描述该人群中RT和pMFC活性之间的关系，或(b)由于样本量相对较小，最近的研究具有高变异性的特点。为了区分这些可能性，我们要求一组相对较大的健康青年（n = 28）执行分心干扰任务-多源干扰任务（MSIT），同时我们用功能性MRI记录他们的大脑活动。在这个相对较大的样本中，模型的两个预测都得到了证实。我们得出的结论是，该模型准确地描述了健康青年pMFC活动与RT之间的关系，但需要进一步的研究来确定与反应冲突无关的过程是否有助于这种关系。
According to the conflict monitoring model of cognitive control, reaction time (RT) in distracter interference tasks (e.g., the Stroop task) is a more precise index of response conflict than stimulus congruency (incongruent vs. congruent). The model therefore predicts that RT should be a reliable predictor of activity in regions of the posterior medial frontal cortex (pMFC) that are posited to detect response conflict. In particular, pMFC activity should be (a) greater in slow-RT than in fast-RT trials within a given task condition (e.g., congruent) and (b) equivalent in RT-matched trials from different conditions (i.e., congruent and incongruent trials). Both of these effects have been observed in functional magnetic resonance imaging (MRI) studies of adults. However, neither effect was observed in a recent study of healthy youth, suggesting that (a) the model does not accurately describe the relationship between RT and pMFC activity in this population or (b) the recent study was characterized by high variability due to a relatively small sample size. To distinguish between these possibilities, we asked a relatively large group of healthy youth (n = 28) to perform a distracter interference task - the multi-source interference task (MSIT) - while we recorded their brain activity with functional MRI. In this relatively large sample, both of the model’s predictions were confirmed. We conclude that the model accurately describes the relationship between pMFC activity and RT in healthy youth, but that additional research is needed to determine whether processes unrelated to response conflict contribute to this relationship.
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