Habitual alcohol seeking: modeling the transition from casual drinking to addiction.

Habitual alcohol seeking: modeling the transition from casual drinking to addiction.
复制标题

寻求习惯性酒精:建模从休闲饮酒到成瘾的过渡。

DOI:
10.1016/j.neubiorev.2014.08.012
复制
发表时间:
2014-11
影响因子:
8.2
通讯作者:
Taylor, Jane R.
Taylor, Jane R.
中科院分区:
医学1区
文献类型:
--
作者:
Barker, Jacqueline M.;Taylor, Jane R.

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The transition from goal-directed actions to habitual ethanol seeking models the development of addictive behavior that characterizes alcohol use disorders. The progression to habitual ethanol-seeking behavior occurs more rapidly than for natural rewards, suggesting that ethanol may act on habit circuit to drive the loss of behavioral flexibility. This review will highlight recent research that has focused on the formation and expression of habitual ethanol seeking, and the commonalities and distinctions between ethanol and natural reward-seeking habits, with the goal of highlighting important, understudied research areas that we believe will lead toward the development of novel treatment and prevention strategies for uncontrolled drinking.
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