Otolithic information is required for homing in the mouse.
Otolithic information is required for homing in the mouse.
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DOI：
10.1002/hipo.22410
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发表时间：
2015-08
期刊：
影响因子：
3.5
通讯作者：
Wallace, Douglas G.
中科院分区：
文献类型：
--
作者：
Yoder, Ryan M.;Goebel, Elizabeth A.;Koeppen, Jenny R.;Blankenship, Philip A.;Blackwell, Ashley A.;Wallace, Douglas G.
导航和潜在的大脑信号会受到各种不同的异素和独特线索的影响，这取决于环境条件和任务要求。视觉地标通常在熟悉的环境中控制导航，但在没有地标的情况下，自我运动线索能够相对准确地引导导航。这些自我运动线索包括来自前庭系统的信号，并且可能起源于半规管或耳石器官。在这里，我们测试了耳石器时代对黑暗和光明中食物囤积任务导航的贡献。黑暗测试阻止使用视觉线索，从而有利于使用自我运动信息，而光测试允许使用视觉和非视觉线索。在黑暗中，倾斜的小鼠在向外的旅程中停留的时间较短，并作出更多的迂回回家的旅程比对照组小鼠;标题错误，行程持续时间和峰值错误倾斜的小鼠比对照组更大。在光线下，倾斜的小鼠也表现出更多的迂回回家的旅程，但似乎纠正错误的旅程中，标题错误，行程持续时间，和峰值错误组之间是相似的。这些结果表明，来自耳石器官的信号是必要的准确归巢性能在小鼠中，在非视觉环境中的贡献最大。
Navigation and the underlying brain signals are influenced by various allothetic and idiothetic cues, depending on environmental conditions and task demands. Visual landmarks typically control navigation in familiar environments but, in the absence of landmarks, self-movement cues are able to guide navigation relatively accurately. These self-movement cues include signals from the vestibular system, and may originate in the semicircular canals or otolith organs. Here, we tested the otolithic contribution to navigation on a food-hoarding task in darkness and in light. The dark test prevented the use of visual cues and thus favored the use of self-movement information, whereas the light test allowed the use of both visual and non-visual cues. In darkness, tilted mice made shorter-duration stops during the outward journey, and made more circuitous homeward journeys than control mice; heading error, trip duration, and peak error were greater for tilted mice than for controls. In light, tilted mice also showed more circuitous homeward trips, but appeared to correct for errors during the journey; heading error, trip duration, and peak error were similar between groups. These results suggest that signals from the otolith organs are necessary for accurate homing performance in mice, with the greatest contribution in non-visual environments.
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影响因子：
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