MouseBook: an integrated portal of mouse resources.

MouseBook: an integrated portal of mouse resources.
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DOI:
10.1093/nar/gkp867
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发表时间:
2010-01
影响因子:
14.9
通讯作者:
Mallon AM
Mallon AM
中科院分区:
生物学2区
文献类型:
--
作者:
Blake A;Pickford K;Greenaway S;Thomas S;Pickard A;Williamson CM;Adams NC;Walling A;Beck T;Fray M;Peters J;Weaver T;Brown SD;Hancock JM;Mallon AM

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MouseBook(http://www.mousebook.org)数据库和网络门户网站)提供了关于突变小鼠品系的信息,这些突变小鼠品系在MRC Harwell作为活的或冷冻保存的库存保存。MouseBook门户将来自MRC Harwell库存资源和其他Harwell数据库的精选信息与来自外部数据资源的信息相结合,以提供超出其他途径(如国际鼠标污渍资源(IMSR))可获得的增值信息。可以使用直观的Google风格的自由文本搜索或使用哺乳动物表型(MP)本体树结构来搜索MouseBook。文本搜索可以是关于基因、等位基因、菌株识别符(例如MGI ID)或表型术语,并由术语类型的自动识别和数据库涵盖的基因和等位基因名称的自动补全来辅助。结果以选项卡格式返回,提供从MouseBook中的每个目录标识的分类结果。每个目录的单独结果行包括关于基因、等位基因、染色体位置和表型的信息,并提供一个简单的点击链接,以获得进一步的信息以及对菌株进行排序。MouseBook的基础设施是可扩展的,允许添加额外的数据源,并允许其他网站通过MouseBook直接访问其数据。
The MouseBook (http://www.mousebook.org) databases and web portal provide access to information about mutant mouse lines held as live or cryopreserved stocks at MRC Harwell. The MouseBook portal integrates curated information from the MRC Harwell stock resource, and other Harwell databases, with information from external data resources to provide value-added information above and beyond what is available through other routes such as International Mouse Stain Resource (IMSR). MouseBook can be searched either using an intuitive Google style free text search or using the Mammalian Phenotype (MP) ontology tree structure. Text searches can be on gene, allele, strain identifier (e.g. MGI ID) or phenotype term and are assisted by automatic recognition of term types and autocompletion of gene and allele names covered by the database. Results are returned in a tabbed format providing categorized results identified from each of the catalogs in MouseBook. Individual result lines from each catalog include information on gene, allele, chromosomal location and phenotype, and provide a simple click-through link to further information as well as ordering the strain. The infrastructure underlying MouseBook has been designed to be extensible, allowing additional data sources to be added and enabling other sites to make their data directly available through MouseBook.
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发表时间: 2009-01
影响因子: 14.9
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