Effects of adult age and blood pressure on executive function and speed of processing.

Effects of adult age and blood pressure on executive function and speed of processing.
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DOI:
10.1080/03610731003613482
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发表时间:
2010-04
影响因子:
1.8
通讯作者:
Madden DJ
Madden DJ
中科院分区:
医学4区
文献类型:
--
作者:
Bucur B;Madden DJ

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以往的研究表明,长期血压升高对认知的影响与成人年龄有相互作用,但相关的认知过程并没有很好的定义。在这项横断面研究中,使用年龄、受教育年限和性别相匹配的样本,134名血压正常(n = 71)或长期血压高(n = 63)的个体被分为年轻(19-39岁)、中年(41-58岁)和老年(60-79岁)组。使用受试者间方差分析,对种族和受教育年限进行协变,执行功能和感知速度的综合测量都显示出与年龄相关的下降。然而,执行功能测量与高血压老年人的差异下降有关。即使在执行功能得分随速度共变的情况下,这一结果仍然成立,表明血压升高对执行功能有独立的、与年龄相关的影响。
Previous research has established that the effects of chronically increased blood pressure (BP) on cognition interact with adult age, but the relevant cognitive processes are not well defined. In this cross sectional study, using a sample matched for age, years of education, and sex, 134 individuals with either normal BP (n = 71) or chronically high BP (n = 63) were categorized into younger (19-39 years), middle-aged (41-58 years), and older (60-79 years) groups. Using a between-subjects ANOVA, covarying for race and years of education, composite measures of executive function and perceptual speed both exhibited age-related decline. The executive function measure, however, was associated with a differential decline in high BP older adults. This result held even when the executive function scores were covaried for speed, demonstrating an independent, age-related effect of higher BP on executive function.
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