The differential effects of unihemispheric and bihemispheric tDCS over the inferior frontal gyrus on proactive control.
The differential effects of unihemispheric and bihemispheric tDCS over the inferior frontal gyrus on proactive control.
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DOI：
10.1016/j.neures.2017.08.005
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发表时间：
2018-05
影响因子：
2.9
通讯作者：
Carvalho S
中科院分区：
文献类型：
--
作者：
Leite J;Gonçalves ÓF;Pereira P;Khadka N;Bikson M;Fregni F;Carvalho S
本研究探讨了额下回（IFG）双侧半球和单侧半球经颅直流电刺激（tDCS）对前摄控制的影响。16名受试者随机接受（i）双侧半球tDCS，右侧IFG的阳极电极为35 cm 2，左侧IFG的阴极电极为35 cm 2，或（ii）单侧半球tDCS，右侧IFG的阳极电极为35 cm 2，左侧IFG的电极为100 cm 2，或（iii）假tDCS，同时执行优势抑制任务。在转换成本方面存在显著的速度-准确性权衡效应：与双半球和假tDCS相比，单半球tDCS的准确性显著降低，而与双半球和假tDCS相比，反应时间增加。计算模型显示了双半球tDCS导联的对称场强，以及单半球tDCS导联的不对称场强。本研究证实，rIFG上的半球tDCS对反应抑制具有显著影响。缺乏双半球tDCS的结果为本研究带来了两个重要的发现：（i）左侧IFG似乎也与抑制反应控制密切相关，（ii）这些结果强调了在选择电极导联时考虑tDCS双重效应的重要性。
This study examined the effects of bihemispheric and unihemispheric transcranial Direct Current Stimulation (tDCS) over the inferior frontal gyrus (IFG) on proactive control. Sixteen participants were randomized to receive (i) bihemispheric tDCS, with a 35 cm2 anodal electrode of the right IFG and a 35 cm2 cathode electrode of left IFG or (ii) unihemispheric tDCS, with a 35 cm2 anodal electrode of the right IFG and a 100 cm2 electrode of the left IFG or (iii) sham tDCS, while performing a prepotent inhibition task. There were significant speed-accuracy tradeoff effects in terms of switch costs: unihemispheric tDCS significantly decreased the accuracy when compared to bihemispheric, and sham tDCS, while increased response time when comparing to bihemispheric and sham tDCS. The computational model showed a symmetrical field intensity for the bihemispheric tDCS montage, and an asymmetrical for the unihemispheric tDCS montage. This study confirms that unihemispheric tDCS over the rIFG has a significant impact on response inhibition. The lack of results of bihemispheric tDCS brings two important findings for this study: (i) left IFG seems to be also critically associated with inhibitory response control, and (ii) these results highlight the importance of considering the dual effects of tDCS when choosing the electrode montage.
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影响因子：
3.7
作者：
Cunillera T;Fuentemilla L;Brignani D;Cucurell D;Miniussi C
通讯作者：
Miniussi C
DOI：
10.1073/pnas.96.14.8301
发表时间：
1999-07-06
影响因子：
11.1
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影响因子：
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作者：
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通讯作者：
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影响因子：
2
作者：
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通讯作者：
Lavidor, Michal