Dietary habits and risk of lung cancer death in a large-scale cohort study (JACC Study) in Japan by sex and smoking habit.
Dietary habits and risk of lung cancer death in a large-scale cohort study (JACC Study) in Japan by sex and smoking habit.
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DOI：
10.1111/j.1349-7006.2001.tb02148.x
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发表时间：
2001-12
期刊：
影响因子：
--
通讯作者：
Ohno Y
中科院分区：
文献类型：
--
作者：
Ozasa K;Watanabe Y;Ito Y;Suzuki K;Tamakoshi A;Seki N;Nishino Y;Kondo T;Wakai K;Ando M;Ohno Y
肺癌已经增加，是日本男性癌症死亡的主要原因。本研究通过性别和吸烟习惯评估了饮食习惯与肺癌死亡风险的关系。在日本合作队列研究（JACC）中，一个在1988-90年建立的队列，由42 940名男性和55 308名女性组成，观察了截至1997年底的肺癌死亡人数。在观察期间，446名男性和126名女性死于肺癌。使用自我管理的食物频率问卷作为基线调查。饮食因素的风险比采用考克斯比例风险模型计算。在男性中，大量摄入火腿和香肠、奶酪、绿色叶蔬菜、橙子和其他水果可显著降低肺癌死亡风险，且呈剂量依赖性。在女性中，大量摄入味噌汤、火腿和香肠以及肝脏显著且几乎呈剂量依赖性地增加了风险。富含抗氧化剂和致癌物质的蔬菜和水果降低了男性吸烟者肺癌死亡的风险，而不是女性非吸烟者。在女性非吸烟者中的研究结果与高脂肪摄入增加肺癌风险的假设部分一致，特别是腺癌。
Lung cancer has increased and is the leading cause of cancer death among Japanese males. The associations of dietary habits with the risk of lung cancer death were evaluated by sex and smoking habits in this study. In the Japan Collaborative Cohort (JACC) Study, a cohort established in 1988–90 and consisting of 42 940 males and 55 308 females was observed for lung cancer deaths up to the end of 1997. During the observation period, 446 males and 126 females died of lung cancer. A self‐administered food frequency questionnaire was used as the baseline survey. Hazard ratios for dietary factors were calculated by Cox's proportional hazards model. Among males, a high intake of ham and sausages, cheese, green‐leafy vegetables, oranges, and other fruits significantly and dose‐dependently decreased the risk of lung cancer death. Among females, a high intake of miso‐soup, ham and sausages, and liver significantly and almost dose‐dependently increased the risk. Vegetables and fruits rich in antioxidative and carcinogenic agents reduced the risk of lung cancer deaths among male smokers more than among female nonsmokers. The results among female nonsmokers were partially consistent with the hypothesis that high fat consumption increases the risk of lung cancer, especially that of adenocarcinoma.
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DOI：
10.1111/j.1349-7006.1993.tb02018.x
发表时间：
1993-06-01
期刊：
JAPANESE JOURNAL OF CANCER RESEARCH
影响因子：
--
作者：
GAO, CM;TAJIMA, K;INOUE, M
通讯作者：
INOUE, M
影响因子：
2.4
作者：
SOBUE, T;SUZUKI, T;FUJIMOTO, I
通讯作者：
FUJIMOTO, I
影响因子：
2.4
作者：
Veierod, MB;Laake, P;Thelle, DS
通讯作者：
Thelle, DS
DOI：
10.1093/jnci/85.23.1906
发表时间：
1993-12-01
期刊：
JOURNAL OF THE NATIONAL CANCER INSTITUTE
影响因子：
--
作者：
ALAVANJA, MCR;BROWN, CC;BROWNSON, RC
通讯作者：
BROWNSON, RC
DOI：
10.1093/jnci/86.1.33
发表时间：
1994-01-05
期刊：
JOURNAL OF THE NATIONAL CANCER INSTITUTE
影响因子：
--
作者：
MAYNE, ST;JANERICH, DT;MCKNEALLY, MF
通讯作者：
MCKNEALLY, MF