What might have been? The role of the ventromedial prefrontal cortex and lateral orbitofrontal cortex in counterfactual emotions and choice.
What might have been? The role of the ventromedial prefrontal cortex and lateral orbitofrontal cortex in counterfactual emotions and choice.
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DOI：
10.1016/j.neuropsychologia.2013.10.026
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发表时间：
2014-02
期刊：
影响因子：
2.6
通讯作者：
Mellers, Barbara A.
中科院分区：
文献类型：
--
作者：
Levens, Sara M.;Larsen, Jeff T.;Bruss, Joel;Tranel, Daniel;Bechara, Antoine;Mellers, Barbara A.
当人们将实际结果与在不同选择下会出现的更好结果进行比较时，就会出现反事实的遗憾感。我们调查了腹内侧前额叶皮层（VMPFC）和外侧眶额叶皮层（LOFC）受损的个体的选择，以了解他们的情绪反应是否对后悔敏感。参与者在赌博之间做出选择，每个赌博都有货币结果。在每一次选择之后，受试者都要了解两次赌博的结果，并评估他们对结果的情绪反应。正常受试者和病变对照组受试者倾向于做出更好的选择，并报告了对后悔比较敏感的决策后情绪。VMPFC患者倾向于做出更糟糕的选择，与我们的预测相反，他们报告的情绪对后悔比较敏感。相比之下，LOFC患者做出了更好的选择，但报告的情绪反应是不敏感的遗憾比较。我们认为VMPFC参与了选择和指导未来选择的预期情绪之间的关联，而LOFC则参与了选择之后的经验情绪，这些情绪可能表明需要行为改变。
Counterfactual feelings of regret occur when people make comparisons between an actual outcome and a better outcome that would have occurred under a different choice. We investigated the choices of individuals with damage to the ventral medial prefrontal cortex (VMPFC) and the lateral orbital frontal cortex (LOFC) to see whether their emotional responses were sensitive to regret. Participants made choices between gambles, each with monetary outcomes. After every choice, subjects learned the consequences of both gambles and rated their emotional response to the outcome. Normal subjects and lesion control subjects tended to make better choices and reported post-decision emotions that were sensitive to regret comparisons. VMPFC patients tended to make worse choices, and, contrary to our predictions, they reported emotions that were sensitive to regret comparisons. In contrast, LOFC patients made better choices, but reported emotional reactions that were insensitive to regret comparisons. We suggest the VMPFC is involved in the association between choices and anticipated emotions that guide future choices, while the LOFC is involved in experienced emotions that follow choices, emotions that may signal the need for behavioral change.
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影响因子：
3.2
作者：
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影响因子：
16.2
作者：
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影响因子：
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作者：
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DOI：
10.1098/rstb.1996.0125
发表时间：
1996-10-29
影响因子：
6.3
作者：
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通讯作者：
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