Anorexia nervosa, neuroimaging research, and the contextual salience of food cues: The food approach-avoidance conundrum.

Anorexia nervosa, neuroimaging research, and the contextual salience of food cues: The food approach-avoidance conundrum.
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DOI:
10.1002/eat.22883
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发表时间:
2018-08
期刊:
The International journal of eating disorders
影响因子:
--
通讯作者:
Strigo IA
Strigo IA
中科院分区:
其他
文献类型:
--
作者:
Murray SB;Strigo IA

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神经性厌食症(AN)的特点是回避和对食物摄入的明显恐惧,但矛盾的是,AN患者经常表现出接近食物的行为,从事食物购物或准备活动,这些活动被描述为奖励。这种接近-回避的难题是非常重要的,因为神经影像学研究继续探索与核心AN精神病理学相关的机制。这个想法值得研究讨论的概念,神经影像学研究依赖于食物提示的演示范例可能是方法上的缺陷,没有指定的上下文显着性的食物提示的范例。食物线索的评价可能会随着一个人的进食意图而不同,因此,神经成像研究没有指定食物线索的上下文显著性(即,吃或不吃)可能混淆两个明显不同的过程。
Anorexia nervosa (AN) is characterized by an avoidance and marked apprehension around food intake, yet paradoxically, those with AN often display approach behaviors to food, engaging in food shopping or preparation activities which are described as rewarding. This approach–avoidance conundrum is of much importance as neuroimaging studies continue to probe mechanisms relating to core AN psychopathology. This Idea Worth Researching discusses the notion that neuroimaging studies relying on food cue presentation paradigms may be methodologically flawed without specifying the contextual salience of the food cues presented in paradigms. The appraisal of food cues may diverge as a function of one’s intent-to-eat, and thus, neuroimaging studies not specifying the contextual salience of food cues (i.e., intent-to-eat or not) may confound two distinctly different processes.
在大鼠和人类中持续的恐惧:恐惧与焦虑中的杏仁核的作用。
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