Effects of dietary galactooligosaccharide on growth, antioxidants, immunity, intestinal morphology and disease resistance against Aeromons hydrophila in juvenile hybrid sturgeon (Acipenser baerii♀ × A. schrenckii♂)
Effects of dietary galactooligosaccharide on growth, antioxidants, immunity, intestinal morphology and disease resistance against Aeromons hydrophila in juvenile hybrid sturgeon (Acipenser baerii♀ × A. schrenckii♂)
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膳食低聚半乳糖对杂交鲟幼鱼（Acipenser baerii – A. schrenckii）生长、抗氧化剂、免疫、肠道形态和对嗜水气单胞菌抗病性的影响
DOI：
10.1016/j.aqrep.2022.101097
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发表时间：
2022-04
影响因子：
3.7
通讯作者：
Denghang Yu
中科院分区：
文献类型：
--
作者：
Hongsen Xu;Yingbing Su;Lin Zhang;Tie Tian;Ruiping Xu;Haoran Sun;Fuguo Liu;Bing Hu;Jin Wei;Jun Liu;Denghang Yu
研究了饲料中添加半乳低聚糖(GOS)对杂交鲟鱼(Acipenser baerii♀×A.Schrenckii♂)生长、抗氧化能力、免疫力、肠道形态及对嗜水气单胞菌抗性的影响。将360尾鱼随机分成12个水族箱，在饲料中分别添加0%、1%、3%和5%浓度的GOS(分别为对照组、GOS1、GOS3和GOS5)，饲养8周。然后，每组30条鱼被用a攻击。在接下来的15天里，记录了死亡率。结果表明，投喂GOS饲料的鲟鱼最终体重(FBW)、增重(WG)、特定生长率(SGR)和饲料转化率(FCR)均有显著差异。投喂GOS饲料的鲟鱼血清中溶菌酶、酸性磷酸酶、碱性磷酸酶和髓过氧化物酶活性均高于对照组。投喂GOS饲料的鱼肝组织中的超氧化物歧化酶、过氧化氢酶和谷胱甘肽过氧化物酶活性显著升高，丙二醛含量显著降低。添加GOS组的中肠肌层厚度、绒毛和微绒毛高度以及中肠杯状细胞数显著增加。在螺旋瓣中，补充任何剂量的GOS都能明显增加肌肉厚度、绒毛高度和杯状细胞，而绒毛宽度和隐窝深度相对不变。饲料中添加果寡糖可降低IL-1mRNA和IL-8mRNA水平，增加β-α基因的表达。挑战测试中有一项。以剂量依赖的方式给予GOS可降低死亡率，投喂GOS5饲料的鱼的相对存活率最高(36.67±91.92%)。研究认为，添加3%的GOS可提高仔猪的生长性能、抗氧化能力和免疫力，调节肠道形态，增强对A的抵抗力。亲水性杂交鲟鱼。
The present study investigated the effects of dietary galactooligosaccharide (GOS) supplementation on growth, antioxidant capacity, immunity, intestinal morphology and resistance toAeromons hydrophilaof hybrid sturgeon (Acipenser baerii♀×A. schrenckii♂). A total number of 360 fish were randomly distributed into 12 aquaria and fed diets supplemented with GOS at 0%, 1%, 3% and 5% concentrations (designated as control, GOS1, GOS3 and GOS5) for 8 weeks. Then 30 fish from each group were intraperitoneally challenged withA. hydrophila, and mortality was recorded for the next 15 days. The results showed that there were significant differences of final body weight (FBW), weight gain (WG), specific growth rate (SGR) and feed conversion ratio (FCR) in sturgeon fed GOS diets. The lysozyme, ACP, AKP and MPO activities in sturgeon serum fed GOS diets were higher than those with control diet. Significant increase of SOD, CAT and GSH-PXcapacity and remarkably decrease of MDA content were observed in liver of fish fed GOS diets. Remarkable enhancement of muscular thickness, villus and microvilli height, and goblet cells in mid intestine was observed in GOS supplemented groups. In spiral valve, supplementation of any quantities of GOS promoted an evident increase in the muscular thickness, villus height and goblet cells, while the villus width and crypt depth were relatively invariant. The IL-1β and IL-8 mRNA levels were decreased and TNF-α gene expression was increased by dietary GOS. The challenge test withA. hydrophilaresulted in lower mortalities by GOS administration in a dose-dependent manner and the highest relative percent survival (36.67 ± 1.92%) was observed in fish fed GOS5 diet. The study concludes that GOS inclusion at the rate of 3% is recommended to increase the growth performance, antioxidant capability and immunity as well as regulate intestinal morphology and promote resistance againstA. hydrophilain hybrid sturgeon.
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影响因子：
0.9
作者：
By R. Li;Y. Zou;Q. Wei
通讯作者：
By R. Li;Y. Zou;Q. Wei
影响因子：
4.7
作者：
S. MİŞE YONAR
通讯作者：
S. MİŞE YONAR
影响因子：
0.9
作者：
Q. Wei;Y. Zou;Ping Li;L. Li
通讯作者：
Q. Wei;Y. Zou;Ping Li;L. Li
DOI：
10.1002/9781118897263.ch14
发表时间：
2014-09
期刊：
--
影响因子：
--
作者：
E. Ringø;A. Dimitroglou;S. Hoseinifar;S. Davies
通讯作者：
E. Ringø;A. Dimitroglou;S. Hoseinifar;S. Davies
影响因子：
4.5
作者：
Ferreira, M;Moradas-Ferreira, P;Reis-Henriques, MA
通讯作者：
Reis-Henriques, MA