Improved ion optics for introduction of ions into a 9.4-T Fourier transform ion cyclotron resonance mass spectrometer.

Improved ion optics for introduction of ions into a 9.4-T Fourier transform ion cyclotron resonance mass spectrometer.
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DOI:
10.1002/jms.3523
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发表时间:
2015-01
影响因子:
2.3
通讯作者:
Marshall, Alan G.
Marshall, Alan G.
中科院分区:
化学4区
文献类型:
--
作者:
Chen, Yu;Leach, Franklin E., III;Kaiser, Nathan K.;Dang, Xibei;Ibrahim, Yehia M.;Norheim, Randolph V.;Anderson, Gordon A.;Smith, Richard D.;Marshall, Alan G.

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我们9.4 T FT-ICR质谱仪的离子源和传递光学的增强导致离子传输效率的提高,在MS和MS/MS水平上对复杂混合物进行更敏感的质量测量。管状透镜/掠光器已被双离子漏斗取代,随后的八爪器被四极杆取代,以减少离子云在传输到质量选择四极杆之前的径向膨胀。到达ICR电池的离子数量,对于漏斗/四极相对于管透镜/撇子/八极增加了一个数量级。
Enhancements to the ion source and transfer optics of our 9.4 T FT-ICR mass spectrometer have resulted in improved ion transmission efficiency for more sensitive mass measurement of complex mixtures at the MS and MS/MS levels. The tube lens/skimmer has been replaced by a dual ion funnel and the following octopole by a quadrupole for reduced ion cloud radial expansion before transmission into a mass-selective quadrupole. The number of ions that reach the ICR cell is increased by an order of magnitude for the funnel/quadrupole relative to the tube lens/skimmer/octopole.
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