Lifestyle factors associated with cognitive functioning in breast cancer survivors.
Lifestyle factors associated with cognitive functioning in breast cancer survivors.
复制标题
与乳腺癌幸存者认知功能相关的生活方式因素。
DOI：
10.1002/pon.3626
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发表时间：
2015-06
期刊：
影响因子：
3.6
通讯作者：
Patterson, Ruth E.
中科院分区：
文献类型：
--
作者：
Hartman, Sheri J.;Marinac, Catherine R.;Natarajan, Loki;Patterson, Ruth E.
Weight, physical activity, and sleep are modifiable lifestyle factors that impact cognitive functioning in non-cancer populations, but have yet to be examined in cancer survivors. The aim of the study was to assess the relationship of obesity, physical activity, and sleep, with cognitive functioning among breast cancer survivors. Participants were 136 early-stage post-menopausal breast cancer survivors who completed an assessment of neuropsychological testing, height, weight, physical activity and sleep. Linear regression models examined the associations of the seven neuropsychological domains with obesity, physical activity, and sleep. Logistic regression models examined odd of impairment in each domain. All models controlled for breast cancer treatment variables and relevant demographic and clinical variables. Obese participants had significantly worse performance (β=−5.04, SE=2.53) and were almost 3 times more likely to be impaired (OR=2.87; 95% CI:1.02–8.10) on the Information Processing domain. The highest tertile of physical activity was significantly related to better performance on the Executive Functioning domain (β=5.13, SE=2.42) and Attention domain (β=4.26, SE=2.07). The middle tertile of physical activity was significantly related to better performance (β=9.00, SE=3.09) and decreased odds of impairment (OR=0.89, 95% CI:0.07–0.91) on the Visual Spatial domain. More hours of sleep per night was significantly associated with better performance (β = 2.69, SE=0.98) and decreased odds of impairment (OR=0.52; 95% CI:0.33–0.82) on the Verbal Functioning domain. These findings suggest that obesity, physical activity, and sleep are related to cognitive functioning among breast cancer survivors and have potential to be intervention targets to improve cognitive functioning.
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影响因子：
3.1
作者：
Gunstad, John;Strain, Gladys;Devlin, Michael J.;Wing, Rena;Cohen, Ronald A.;Paul, Robert H.;Crosby, Ross D.;Mitchell, James E.
通讯作者：
Mitchell, James E.
影响因子：
4
作者：
Janelsins MC;Kohli S;Mohile SG;Usuki K;Ahles TA;Morrow GR
通讯作者：
Morrow GR
影响因子：
3.4
作者：
Foster PP;Rosenblatt KP;Kuljiš RO
通讯作者：
Kuljiš RO
影响因子：
2.7
作者：
Goel N;Rao H;Durmer JS;Dinges DF
通讯作者：
Dinges DF
影响因子：
5.6
作者：
Patel, SR;Ayas, NT;Hu, FB
通讯作者：
Hu, FB