Mechanism of reflex regulation of the gastroduodenal function by acupuncture.

Mechanism of reflex regulation of the gastroduodenal function by acupuncture.
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DOI:
10.1093/ecam/nem077
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发表时间:
2008-09
影响因子:
--
通讯作者:
Noguchi, Eitaro
Noguchi, Eitaro
中科院分区:
医学4区
文献类型:
--
作者:
Noguchi, Eitaro

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许多临床研究集中在针灸对消化系统疾病的影响。然而,很少有研究描述这些效应产生的机制。我们介绍了最近关于针刺对麻醉大鼠胃十二指肠功能反射调节机制的一些实验工作。在麻醉大鼠中,已经证明,针刺腹部通过脊髓反射兴奋交感神经,导致运动抑制,而针刺四肢通过脊髓上反射兴奋迷走神经,导致运动增加。它还表明,为了抑制胃动力,腹部的针刺刺激必须足够强,以兴奋传入肋间神经的第VI组纤维。为了增加胃动力,对后肢的针刺刺激必须足够强,以兴奋胫神经的高阈值III组纤维。针刺刺激十二指肠运动的神经机制与刺激胃运动的神经机制涉及相同的身体部位和刺激强度。关于潜在机制的理论提出了躯体自主神经反射和通过内源性阿片样物质的反应等,但没有明确的结论。
Many clinical studies focus on the effects of acupuncture on digestive disorders. However, few studies describe the mechanism by which these effects are produced. We present some recent experimental work on the mechanism of acupuncture for reflex regulation of gastroduodenal function in anesthetized rats. In anesthetized rats, it has been proven that acupuncture to the abdomen excites sympathetic nerves via spinal reflexes causing inhibition of motilities while acupuncture of limbs excites vagus nerves via supraspinal reflexes causing an increase in the motilities. It has also been shown that in order to inhibit gastric motilities, acupuncture stimulation of the abdomen must be strong enough to excite group VI fibers of the afferent intercostal nerves. To increase gastric motilities, acupuncture stimulation to hind limbs must be strong enough to excite the high-threshold group III fibers of tibial nerves. It has also been shown that the neural mechanism of duodenal motility stimulation by acupuncture involves the same body regions and intensity of stimulation as that of gastric motilities. Theories regarding the underlying mechanism have proposed somato-autonomic reflexes and responses via endogenous opioids, etc., but without definitive conclusions.
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