The interaction of lipids and inflammatory markers predict negative symptom severity in patients with schizophrenia.
The interaction of lipids and inflammatory markers predict negative symptom severity in patients with schizophrenia.
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DOI:
10.1038/s41537-021-00179-8
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发表时间:
2021-10-20
影响因子:
5.4
通讯作者:
Duncan E
中科院分区:
文献类型:
--
作者:
Goldsmith DR;Massa N;Miller BJ;Miller AH;Duncan E
Finding biological predictors and novel mechanisms underlying negative symptoms of schizophrenia is of significant importance given the lack of effective treatments. Increasing data support a role for metabolic dysfunction and inflammation in reward processing deficits in psychiatric illness. Herein, we found an interaction between lipids and inflammation as a predictor of worse negative symptom severity in individuals with schizophrenia. Future studies may seek to further elucidate this relationship and thereby reveal novel treatment targets for negative symptoms.
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作者:
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通讯作者:
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