Development and Evaluation of a Manganese and Iron Food Frequency Questionnaire for Pediatrics.
Development and Evaluation of a Manganese and Iron Food Frequency Questionnaire for Pediatrics.
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DOI：
10.3390/ijerph14091060
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发表时间：
2017-09-14
影响因子：
--
通讯作者：
Haynes EN
中科院分区：
文献类型：
--
作者：
Zipkin FB;Falciglia GA;Kuhnell P;Haynes EN
锰（Mn）是一种必需的营养素，但过量接触会导致神经毒性。考虑到饮食中锰的重要性，特别是在儿童的生长发育过程中，有必要量化可能暴露于工业锰来源的人群的膳食锰摄入量。膳食中Mn的吸收与铁（Fe）的储存呈负相关，但目前还没有食物频率问卷（FFQ）来评估膳食中Mn和Fe的摄入量。该研究的目的是通过比较估计的锰和铁的摄入量与生物标志物：血液和头发中的锰和血清中的铁，来开发和评估FFQ测量儿科饮食中锰和铁摄入量的有效性。本研究利用了居住在俄亥俄州根西县的社区积极研究暴露研究（CARES）人口的一个子集。膳食锰与血锰和发锰均无相关性；饲粮Mn与血清铁蛋白呈极显著相关，相关系数为0.51,p < 0.01。饲粮铁与血清铁蛋白也极显著相关，相关系数为0.51,p < 0.01。该FFQ是测定血清铁蛋白对铁摄入量的有效工具；然而，锰摄入量与血锰和发锰均无相关性。
Manganese (Mn) is an essential nutrient, but overexposure can lead to neurotoxicity. Given the essentiality of Mn in the diet, particularly during children’s growth and development, it is imperative to quantify dietary Mn intake in populations that may be exposed to industrial sources of Mn. Dietary absorption of Mn is inversely associated with iron (Fe) stores, yet there is currently no food frequency questionnaire (FFQ) to assess dietary Mn and Fe intake. The study objective was to develop and evaluate the validity of a FFQ to measure dietary Mn and Fe intake in pediatrics by comparing the estimated intakes of Mn and Fe with biomarkers: Mn in blood and hair and Fe in serum. This study utilized a subset of the Communities Actively Researching Exposure Study (CARES) population residing in Guernsey County, Ohio. Dietary Mn was not correlated with either blood or hair Mn; however, dietary Mn and serum ferritin were significantly correlated, with a correlation coefficient of 0.51, p < 0.01. Moreover, dietary Fe and serum ferritin were also significantly correlated, with a correlation coefficient of 0.51, p < 0.01. This FFQ is a valid measurement tool for Fe intake as measured by serum ferritin; however, Mn intake did not correlate with either blood or hair Mn.
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影响因子：
10.4
作者：
Claus Henn B;Schnaas L;Ettinger AS;Schwartz J;Lamadrid-Figueroa H;Hernández-Avila M;Amarasiriwardena C;Hu H;Bellinger DC;Wright RO;Téllez-Rojo MM
通讯作者：
Téllez-Rojo MM
影响因子：
11.4
作者：
Eastman, Rachel R.;Jursa, Tom P.;Benedetti, Chiara;Lucchini, Roberto G.;Smith, Donald R.
通讯作者：
Smith, Donald R.
DOI：
10.2165/00139709-200625030-00002
发表时间：
2006-01-01
期刊：
Toxicological reviews
影响因子：
--
作者：
Aschner, Michael;Dorman, David C
通讯作者：
Dorman, David C
影响因子：
10.4
作者：
Bouchard MF;Sauvé S;Barbeau B;Legrand M;Brodeur MÈ;Bouffard T;Limoges E;Bellinger DC;Mergler D
通讯作者：
Mergler D
影响因子：
3.8
作者：
Dorman, DC;Struve, MF;Wong, BA
通讯作者：
Wong, BA