The hippocampus and imagining the future: where do we stand?

The hippocampus and imagining the future: where do we stand?
复制标题

DOI:
10.3389/fnhum.2011.00173
复制
发表时间:
2011
影响因子:
2.9
通讯作者:
Schacter DL
Schacter DL
中科院分区:
医学3区
文献类型:
--
作者:
Addis DR;Schacter DL

文献摘要

参考文献

被引文献

相似文献

最近的神经成像研究表明,海马体在想象未来时会参与其中,在某些情况下,比回忆过去时更重要。这种海马体的激活可能反映了将细节重新组合成连贯的场景和/或将这些场景编码到记忆中以供以后使用。然而,最近对记忆丧失和海马损伤患者的未来模拟研究中出现了不一致的结果。因此,海马体是否是未来模拟所必需的仍然是一个悬而未决的问题。在这篇综述中,我们认为从病人的研究和神经影像学文献的结果方面的一个新的框架,突出了三个组成部分的模拟过程:访问情节的细节,重组的细节,和编码模拟。我们试图调和这些差异之间的神经影像学和病人的研究表明,不同的组件的过程中,未来的模拟可能会受到不同的海马损伤。
Recent neuroimaging work has demonstrated that the hippocampus is engaged when imagining the future, in some cases more than when remembering the past. It is possible that this hippocampal activation reflects recombining details into coherent scenarios and/or the encoding of these scenarios into memory for later use. However, inconsistent findings have emerged from recent studies of future simulation in patients with memory loss and hippocampal damage. Thus, it remains an open question as to whether the hippocampus is necessary for future simulation. In this review, we consider the findings from patient studies and the neuroimaging literature with respect to a new framework that highlights three component processes of simulation: accessing episodic details, recombining details, and encoding simulations. We attempt to reconcile these discrepancies between neuroimaging and patient studies by suggesting that different component processes of future simulation may be differentially affected by hippocampal damage.
DOI: 10.1016/j.neuropsychologia.2011.09.021
发表时间: 2011-11
期刊: Neuropsychologia
影响因子: 2.6
作者:
Addis DR;Roberts RP;Schacter DL
通讯作者: Schacter DL
DOI: 10.1016/j.neuropsychologia.2011.03.008
发表时间: 2011-06
期刊: Neuropsychologia
影响因子: 2.6
作者:
Cooper JM;Vargha-Khadem F;Gadian DG;Maguire EA
通讯作者: Maguire EA
DOI: 10.1016/s0166-4328(01)00365-5
发表时间: 2001-12-14
影响因子: 2.7
作者:
Eichenbaum, H
通讯作者: Eichenbaum, H
DOI: 10.1523/jneurosci.6559-10.2011
发表时间: 2011-05-04
影响因子: 5.3
作者:
Benoit, Roland G.;Gilbert, Sam J.;Burgess, Paul W.
通讯作者: Burgess, Paul W.
DOI: 10.1016/j.neuropsychologia.2009.05.018
发表时间: 2009-10-01
期刊: NEUROPSYCHOLOGIA
影响因子: 2.6
作者:
Addis, Donna Rose;Sacchetti, Daniel C.;Schacter, Daniel L.
通讯作者: Schacter, Daniel L.