Characteristics and predictors of persistent symptoms post-COVID-19 in children and young people: a large community cross-sectional study in England.
Characteristics and predictors of persistent symptoms post-COVID-19 in children and young people: a large community cross-sectional study in England.
复制标题
DOI：
10.1136/archdischild-2022-325152
复制
发表时间：
2023-07
影响因子：
5.2
通讯作者：
Ward, Helen
中科院分区：
文献类型：
--
作者：
Atchison, Christina J.;Whitaker, Matthew;Donnelly, Christl A.;Chadeau-Hyam, Marc;Riley, Steven;Darzi, Ara;Ashby, Deborah;Barclay, Wendy;Cooke, Graham S.;Elliott, Paul;Ward, Helen
估计英格兰5-17岁儿童COVID-19后持续症状的患病率及其相关风险因素。系列横断面研究。第10-19轮（2021年3月至2022年3月）社区传播实时评估-1研究（英格兰人口随机样本的月度横断面调查）。社区中5-17岁的儿童。年龄、性别、种族、存在既存健康状况、多重剥夺指数、COVID-19疫苗接种状况和症状发作时英国流行的SARS-CoV-2主要变体。持续症状的患病率，报告为COVID-19后持续≥3个月。总体而言，4.4%（95% CI 3.7至5.1），3173名5-11岁儿童和13.3%（95% CI 12.5 - 14.1）在6886名既往有症状感染的12-17岁儿童中，报告了COVID-19后至少一种持续≥3个月的症状，其中分别有13.5%（95% CI 8.4 - 20.9）和10.9%（95% CI 9.0 - 13.2）的患者报告称，由于症状，他们进行日常活动的能力"大大“降低。持续症状的参与者中最常见的症状是5-11岁儿童的持续咳嗽（27.4%）和头痛（25.4%），以及12-17岁参与者的嗅觉（52.2%）和味觉（40.7%）丧失或改变。较高的年龄和预先存在的健康状况与报告持续症状的几率较高相关。23名5-11岁儿童中有1人和8名12-17岁儿童中有1人报告了持续≥3个月的持续症状，其中9人中有1人报告对日常活动产生了很大影响。
To estimate the prevalence of, and associated risk factors for, persistent symptoms post-COVID-19 among children aged 5–17 years in England. Serial cross-sectional study. Rounds 10–19 (March 2021 to March 2022) of the REal-time Assessment of Community Transmission-1 study (monthly cross-sectional surveys of random samples of the population in England). Children aged 5–17 years in the community. Age, sex, ethnicity, presence of a pre-existing health condition, index of multiple deprivation, COVID-19 vaccination status and dominant UK circulating SARS-CoV-2 variant at time of symptom onset. Prevalence of persistent symptoms, reported as those lasting ≥3 months post-COVID-19. Overall, 4.4% (95% CI 3.7 to 5.1) of 3173 5–11 year-olds and 13.3% (95% CI 12.5 to 14.1) of 6886 12–17 year-olds with prior symptomatic infection reported at least one symptom lasting ≥3 months post-COVID-19, of whom 13.5% (95% CI 8.4 to 20.9) and 10.9% (95% CI 9.0 to 13.2), respectively, reported their ability to carry out day-to-day activities was reduced ‘a lot’ due to their symptoms. The most common symptoms among participants with persistent symptoms were persistent coughing (27.4%) and headaches (25.4%) in children aged 5–11 years and loss or change of sense of smell (52.2%) and taste (40.7%) in participants aged 12–17 years. Higher age and having a pre-existing health condition were associated with higher odds of reporting persistent symptoms. One in 23 5–11 year-olds and one in eight 12–17 year-olds post-COVID-19 report persistent symptoms lasting ≥3 months, of which one in nine report a large impact on performing day-to-day activities.
登录
查看更多内容
DOI：
10.1126/science.abn8347
发表时间：
2022-03-25
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Elliott P;Bodinier B;Eales O;Wang H;Haw D;Elliott J;Whitaker M;Jonnerby J;Tang D;Walters CE;Atchison C;Diggle PJ;Page AJ;Trotter AJ;Ashby D;Barclay W;Taylor G;Ward H;Darzi A;Cooke GS;Chadeau-Hyam M;Donnelly CA
通讯作者：
Donnelly CA
COVID-19 的 50 多种长期影响：系统回顾和荟萃分析。
影响因子：
4.6
作者：
Lopez-Leon S;Wegman-Ostrosky T;Perelman C;Sepulveda R;Rebolledo PA;Cuapio A;Villapol S
通讯作者：
Villapol S
轻度疾病患者的急性后和长期covid-19症状：系统评价。
影响因子：
2.2
作者：
van Kessel SAM;Olde Hartman TC;Lucassen PLBJ;van Jaarsveld CHM
通讯作者：
van Jaarsveld CHM
影响因子：
5.2
作者：
Stephenson T;Allin B;Nugawela MD;Rojas N;Dalrymple E;Pinto Pereira S;Soni M;Knight M;Cheung EY;Heyman I;CLoCk Consortium;Shafran R
通讯作者：
Shafran R
影响因子：
13.8
作者：
Nasserie T;Hittle M;Goodman SN
通讯作者：
Goodman SN