The Chlamydomonas kinesin-like protein FLA10 is involved in motility associated with the flagellar membrane.
The Chlamydomonas kinesin-like protein FLA10 is involved in motility associated with the flagellar membrane.
复制标题
DOI:
10.1083/jcb.131.6.1517
复制
发表时间:
1995-12
影响因子:
7.8
通讯作者:
ROSENBAUM, JL
中科院分区:
文献类型:
--
作者:
KOZMINSKI, KG;BEECH, PL;ROSENBAUM, JL
The Chlamydomonas FLA10 gene was shown to encode a flagellar kinesin- like protein (Walther, Z., M. Vashishtha, and J.L. Hall. 1994. J. Cell Biol. 126:175-188). By using a temperature-sensitive allele of FLA10, we have determined that the FLA10 protein is necessary for both the bidirectional movement of polystyrene beads on the flagellar membrane and intraflagellar transport (IFT), the bidirectional movement of granule-like particles beneath the flagellar membrane (Kozminski, K.G., K.A. Johnson, P. Forscher, and J.L. Rosenbaum. 1993. Proc. Natl. Acad. Sci. (USA). 90:5519-5523). In addition, we have correlated the presence and position of the IFT particles visualized by light microscopy with that of the electron dense complexes (rafts) observed beneath the flagellar membrane by electron microscopy. A role for FLA10 in submembranous or flagellar surface motility is also strongly supported by the immunolocalization of FLA10 to the region between the axonemal outer doublet microtubules and the flagellar membrane.
登录
查看更多内容
影响因子:
5.6
作者:
ALLEN, C;BORISY, GG
通讯作者:
BORISY, GG
影响因子:
19
作者:
Bernstein, Mitchell;Rosenbaum, Joel L.
通讯作者:
Rosenbaum, Joel L.
DOI:
10.1083/jcb.91.3.661
发表时间:
1981-12
期刊:
The Journal of cell biology
影响因子:
--
作者:
Heidemann SR;Landers JM;Hamborg MA
通讯作者:
Hamborg MA
影响因子:
7.8
作者:
Coyne, B;Rosenbaum, J L
通讯作者:
Rosenbaum, J L
影响因子:
64.8
作者:
COLE, DG;CHINN, SW;SCHOLEY, JM
通讯作者:
SCHOLEY, JM