Seroprevalence of Borrelia burgdorferi in Horses Presented for Coggins Testing in Southwest Virginia and Change in Positive Test Results Approximately 1 Year Later.

Seroprevalence of Borrelia burgdorferi in Horses Presented for Coggins Testing in Southwest Virginia and Change in Positive Test Results Approximately 1 Year Later.
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DOI:
10.1111/jvim.13973
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发表时间:
2016-07
影响因子:
2.6
通讯作者:
Hodgson DR
Hodgson DR
中科院分区:
农林科学2区
文献类型:
--
作者:
Funk RA;Pleasant RS;Witonsky SG;Reeder DS;Werre SR;Hodgson DR

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莱姆病可以影响人,狗和马,但人们对它的了解仍然很少,特别是在马身上。确定不同地理区域的马中伯氏疏螺旋体的血清阳性率将使人们能够更好地了解该疾病的流行病学,从而改善对受影响动物的诊断和治疗。确定B的血清阳性率。在弗吉尼亚州西南部的马中发现了伯氏症。从2013年1月至2014年1月,对进行常规Coggins检测的马进行了额外的血液采集,用于莱姆多重试验检测。在收集的492份样品中,使用莱姆多重测定法分析了250份样品。在至少1种外表面蛋白(Osp)检测结果呈阳性的83匹马中,有63匹可在5-17个月后(2014年6月)进行后续检测。33%的马对至少1种Osp的抗体呈阳性结果。外表面蛋白F(OspF)结果阳性的马(14.5 ± 0.79)比OspF结果阴性的马(11.6 ± 0.53)年龄大。在可用于随访试验的马中,63%的结果与初始试验的结果相同。初始和随访测试之间的测试结果无差异。马对B呈血清阳性。burgdorferi在弗吉尼亚州很常见,年龄较大的马比年轻的马更有可能有阳性的OspF测试结果。随访测试表明,大多数在初始测试中呈阳性的马在5-17个月后没有不同的测试结果。
Lyme disease can affect people, dogs, and horses, but it remains poorly understood, especially in the horse. Determining the seroprevalence of Borrelia burgdorferi in horses in different geographic areas will enable better understanding of the epidemiology of the disease, thus improving diagnosis and treatment of affected animals. To determine the seroprevalence of B. burgdorferi in horses in southwest Virginia. Horses presented for routine Coggins testing from January 2013 to January 2014 had additional blood drawn for Lyme Multiplex Assay testing. Of 492 samples collected, 250 samples were analyzed using the Lyme Multiplex Assay. Of the 83 horses that had positive test results to at least 1 outer surface protein (Osp), 63 were available for follow‐up testing 5–17 months later (June 2014). Thirty‐three percent of horses had positive results for antibodies to at least 1 Osp. Horses with a positive outer surface protein F (OspF) result were older (14.5 ± 0.79) than horses with a negative OspF result (11.6 ± 0.53). Of the horses available for follow‐up testing, 63% had the same result as that of the initial test. There was no difference in test result between initial and follow‐up testing. Horses seropositive to B. burgdorferi are common in Virginia, and older horses are more likely to have a positive test result for OspF than younger horses. Follow‐up testing indicated that the majority of horses that were positive on initial testing did not have a different test result 5–17 months later.
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