Pica as an adaptive response: Kaolin consumption helps rats recover from chemotherapy-induced illness.
Pica as an adaptive response: Kaolin consumption helps rats recover from chemotherapy-induced illness.
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DOI：
10.1016/j.physbeh.2009.02.009
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发表时间：
2009-04-20
影响因子：
2.9
通讯作者：
Tordoff, Michael G.
中科院分区：
文献类型：
--
作者：
de Jonghe, Bart C.;Lawler, Maureen P.;Horn, Charles C.;Tordoff, Michael G.
生病时可能会摄入粘土，但对其中原因的研究很少。为了调查食用粘土是否对患病动物有利，我们比较了有或没有使用高岭土的成年雄性大鼠的康复情况。通过注射毒性化疗药物顺铂（ip6 mg/kg）诱导疾病，通过每日食物摄取量、饮水量和体重的变化来评估恢复情况。与注射盐水的对照组相比，注射顺铂的大鼠减少了食物和水的摄入量，体重减轻。然而，那些吃高岭土的人比那些没有吃高岭土的人吃得更多，体重下降得更少。因此，食用粘土似乎是有益的，因为它既可以保护大鼠免受疾病的侵害，也可以促进恢复，并且可能被证明是对其他动物（包括人类）内脏不适的辅助疗法有用。
Clay consumption can occur during illness but there has been little work to understand why. To investigate whether consuming clay confers an advantage to the sick animal, we compared the recovery from illness of adult male rats with or without access to kaolin. Illness was induced by injection of 6 mg/kg, ip, cisplatin, a toxic chemotherapy agent, and recovery was assessed by changes in daily food intake, water intake, and body weight. Relative to saline-injected controls, cisplatin-injected rats reduced food and water intake and lost weight. However, those with access to kaolin ate more food and lost less body weight than did those without access to kaolin. Thus, clay consumption appeared beneficial in that it either protected the rats from illness or enhanced recovery and might prove useful as an adjunct therapy for other animals, including humans, experiencing visceral malaise.
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影响因子：
4.2
作者：
PATTERSON, EC;STASZAK, DJ
通讯作者：
STASZAK, DJ
影响因子：
3.5
作者：
SARR, AB;MAYURA, K;PHILLIPS, TD
通讯作者：
PHILLIPS, TD
影响因子：
4.3
作者：
Singhi, Sunit;Ravishanker, R.;Nath, R.
通讯作者：
Nath, R.
影响因子：
3.8
作者：
Phillips, TD
通讯作者：
Phillips, TD
DOI：
10.1111/j.2517-6161.1995.tb02031.x
发表时间：
1995-01-01
影响因子：
5.8
作者：
BENJAMINI, Y;HOCHBERG, Y
通讯作者：
HOCHBERG, Y