A randomized controlled trial of a cognitive rehabilitation intervention for persons with multiple sclerosis.

A randomized controlled trial of a cognitive rehabilitation intervention for persons with multiple sclerosis.
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对多发性硬化症患者进行认知康复干预的随机对照试验。

DOI:
10.1177/0269215511434997
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发表时间:
2012-10
影响因子:
3
通讯作者:
Todd A
Todd A
中科院分区:
医学2区
文献类型:
--
作者:
Stuifbergen AK;Becker H;Perez F;Morison J;Kullberg V;Todd A

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探讨计算机辅助认知康复干预——多发性硬化症患者记忆、注意力和问题解决技能(MAPSS-MS)对多发性硬化症(MS)患者认知表现、记忆策略使用、控制症状的自我效能和日常生活活动(ADL)神经心理学能力的可行性和效果。一项随机对照单盲试验,包括治疗组和等待名单对照组。美国西南部。 61 名 MS 患者(34 名接受治疗,27 名等候名单对照)的方便样本(平均年龄 47.9 岁,SD 8.8)。为期八周的 MAPSS-MS 干预计划包括两个组成部分:(a) 每周八次的小组会议,重点是建立认知补偿策略使用的功效;(b) 计算机辅助认知康复计划和家庭培训。在基线、2个月(课后)和5个月时完成了一系列神经心理学性能测试,包括多发性硬化症认知功能最低限度评估(MACFIMS)和自我报告工具(使用记忆策略、控制多发性硬化症的自我效能和ADL神经心理学能力)。随着时间的推移,两组在 MACFIMS 电池中的大多数测量以及 ADL 中的策略使用和神经心理学能力测量上都有显着改善 (p<.05)。在言语记忆测量和补偿记忆策略的使用方面,按时间划分的分数存在显着的交互作用。 MAPSS-MS 干预是可行的并且受到参与者的广泛接受。鉴于干预组使用补偿策略的相对大量增加,它有望增强多发性硬化症患者的认知功能。
To explore the feasibility and effects of a computer-assisted cognitive rehabilitation intervention, Memory, Attention, and Problem Solving Skills for Persons with MS (MAPSS-MS), for persons with multiple sclerosis (MS) on cognitive performance, memory strategy use, self-efficacy for control of symptoms and neuropsychological competence in activities of daily living (ADL). A randomized controlled single-blinded trial with treatment and wait list-control groups. Southwestern United States. Convenience sample of 61 persons (34 treatment, 27 wait list control) with MS (mean age 47.9 years, SD 8.8). The eight-week MAPSS-MS intervention program included two components: (a) eight weekly group sessions focused on building efficacy for use of cognitive compensatory strategies and (b) a computer-assisted cognitive rehabilitation program with home-based training. A neuropsychological battery of performance tests comprising the Minimal Assessment of Cognitive Function in MS (MACFIMS) and self-report instruments (use of memory strategies, self-efficacy for control of MS and neuropsychological competence in ADL) were completed at baseline, 2 months (after classes), and at 5 months. Both groups improved significantly (p<.05) over time on most measures in the MACFIMS battery as well as the measures of strategy use and neuropsychological competence in ADL. There was a significant group by time interaction for scores on the measures of verbal memory and use of compensatory memory strategies. The MAPSS-MS intervention was feasible and well-accepted by participants. Given the large relative increase in use of compensatory strategies by the intervention group, it holds promise for enhancing cognitive function in persons with MS.
DOI: 10.1076/clin.16.3.381.13859
发表时间: 2002-08-01
影响因子: 3.9
作者:
Benedict, RHB;Fischer, JS;Munschauer, F
通讯作者: Munschauer, F
DOI: 10.1212/wnl.41.5.692
发表时间: 1991-05-01
期刊: NEUROLOGY
影响因子: 9.9
作者:
RAO, SM;LEO, GJ;UNVERZAGT, F
通讯作者: UNVERZAGT, F
DOI: 10.1016/j.clineuro.2009.10.019
发表时间: 2010-02-01
影响因子: 1.9
作者:
Goretti, Benedetta;Portaccio, Emilio;Amato, Maria Pia
通讯作者: Amato, Maria Pia
DOI: 10.1155/2006/545860
发表时间: 2006
影响因子: 2.8
作者:
Pierson SH;Griffith N
通讯作者: Griffith N
DOI: 10.1191/135245801678438447
发表时间: 2001-06-01
期刊: MULTIPLE SCLEROSIS
影响因子: --
作者:
Bowen, J;Gibbons, L;Kraft, GH
通讯作者: Kraft, GH