Biofabrication of natural hydrogels for cardiac, neural, and bone Tissue engineering Applications.
Biofabrication of natural hydrogels for cardiac, neural, and bone Tissue engineering Applications.
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DOI：
10.1016/j.bioactmat.2021.03.040
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发表时间：
2021-11
影响因子：
18.9
通讯作者：
Arab-Tehrany E
中科院分区：
文献类型：
--
作者：
Elkhoury K;Morsink M;Sanchez-Gonzalez L;Kahn C;Tamayol A;Arab-Tehrany E
天然水凝胶因其生物相容性、生物可降解性和细胞外基质模拟能力而成为组织工程应用中最有前途的生物材料之一。为了超越传统制造技术的局限性并重现天然组织结构的复杂结构，人们正在使用新颖的生物制造策略（例如纺织技术和三维生物打印）来构建天然水凝胶。这些创新技术在开发各种组织工程应用的先进支架方面发挥着巨大作用。本综述重点介绍了新兴生物制造技术的进展、优点和缺点。此外，还讨论了生物制造的天然水凝胶在心脏、神经和骨组织工程中的新应用。概述了天然水凝胶的不同生物制造技术。讨论了新型生物制造策略的进展、优点和缺点。介绍了生物制造的天然水凝胶在心脏、神经和骨组织工程中的新应用。强调了生物制造支架转化面临的被忽视的挑战及其潜在的解决方案。
Natural hydrogels are one of the most promising biomaterials for tissue engineering applications, due to their biocompatibility, biodegradability, and extracellular matrix mimicking ability. To surpass the limitations of conventional fabrication techniques and to recapitulate the complex architecture of native tissue structure, natural hydrogels are being constructed using novel biofabrication strategies, such as textile techniques and three-dimensional bioprinting. These innovative techniques play an enormous role in the development of advanced scaffolds for various tissue engineering applications. The progress, advantages, and shortcomings of the emerging biofabrication techniques are highlighted in this review. Additionally, the novel applications of biofabricated natural hydrogels in cardiac, neural, and bone tissue engineering are discussed as well. Different biofabrication techniques of natural hydrogels were overviewed. The progress, advantages, and disadvantages of the novel biofabrication strategies were discussed. Novel applications of biofabricated natural hydrogels in cardiac, neural, and bone tissue engineering were presented.. Overlooked challenges facing the translation of biofabricated scaffolds and their potential solutions were highlighted.
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影响因子：
6.7
作者：
Ahadian S;Khademhosseini A
通讯作者：
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影响因子：
14
作者：
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Khademhosseini, Ali
影响因子：
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作者：
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影响因子：
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